Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 14/20 | 0.57 |
| ▸ | BRD2 | P25440 | 5/20 | 0.57 |
| ▸ | CREBBP | Q92793 | 3/20 | 0.57 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.49 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16675743 | 0.84 | BRD4 (0.58) | BRD4BRD2CREBBPFFAR1BRD3 | |
| SCHEMBL20946455 | 0.84 | BRD4 (0.57) | BRD4BRD2CREBBPFFAR1BRD3 | |
| SCHEMBL12881340 | 0.83 | BRD4 (0.59) | BRD4BRD2CREBBPFFAR1BRD3 | |
| SCHEMBL5217255 | 0.82 | BRD4 (0.55) | BRD4BRD2CREBBPFFAR1BRD3 | |
| SCHEMBL12866840 | 0.82 | BRD4 (0.57) | BRD4BRD2CREBBPFFAR1BRD3 | |
| SCHEMBL22775611 | 0.80 | BRD4 (0.60) | BRD4BRD2CREBBPFFAR1BRD3 | |
| SCHEMBL3338755 | 0.80 | HTR7 (0.62) | BRD4BRD2CREBBPFFAR1 | |
| SCHEMBL3340053 | 0.80 | BRD4 (0.52) | BRD4BRD2CREBBPFFAR1BRD3 | |
| SCHEMBL12487 | 0.78 | NPC1 (0.69) | BRD4BRD2CREBBPBRD3NPC1 | |
| SCHEMBL3339883 | 0.77 | BRD4 (0.53) | BRD4BRD2CREBBPFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105198826-A | 3,5-dimethyl isoxazole derivatives, preparation method of derivatives, and application of derivatives as drugs | UNIV CHINA PHARMA | 2015-12-30 | — | — | CN | disclosed |