Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | OXER1 | Q8TDS5 | 2/20 | 0.36 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27627561 | 0.89 | TSHR (0.52) | TSHRLMNAALDH1A1MEN1KMT2A | |
| SCHEMBL9910358 | 0.89 | TSHR (0.52) | TSHRLMNAALDH1A1MEN1KMT2A | |
| SCHEMBL7772114 | 0.83 | CES1 (0.38) | TSHRALDH1A1KEAP1NFE2L2HCAR2 | |
| SCHEMBL9327902 | 0.83 | CES1 (0.38) | TSHRALDH1A1KEAP1NFE2L2HCAR2 | |
| SCHEMBL29220173 | 0.81 | POLB (0.42) | TSHRALDH1A1MEN1KMT2A | |
| SCHEMBL7949525 | 0.81 | POLB (0.42) | TSHRALDH1A1MEN1KMT2A | |
| SCHEMBL10000423 | 0.80 | MGAM (0.41) | TSHRLMNAALDH1A1MEN1KMT2A | |
| SCHEMBL12332891 | 0.80 | MGAM (0.41) | TSHRLMNAALDH1A1MEN1KMT2A | |
| SCHEMBL7772525 | 0.79 | HCAR2 (0.37) | TSHRALDH1A1KEAP1NFE2L2HCAR2 | |
| SCHEMBL6877098 | 0.79 | HCAR2 (0.37) | TSHRALDH1A1KEAP1NFE2L2HCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120258504-A1 | BIOLOGICAL SYNTHESIS OF DIFUNCTIONAL ALKANES FROM CARBOHYDRATE FEEDSTOCKS | CELEXION, LLC (US) | 2012-10-11 | — | — | US | disclosed |
| US-20120164702-A1 | BIOLOGICAL SYNTHESIS OF DIFUNCTIONAL ALKANES FROM CARBOHYDRATE FEEDSTOCKS | CELEXION, LLC (US) | 2012-06-28 | — | — | US | disclosed |
| US-8192976-B2 | Biological synthesis of difunctional alkanes from carbohydrate feedstocks | CELEXION, LLC (US) | 2012-06-05 | — | — | US | disclosed |
| US-8133704-B2 | Biological synthesis of difunctional alkanes from carbohydrate feedstocks | CELEXION, LLC (US) | 2012-03-13 | — | — | US | disclosed |
| US-20110171696-A1 | Biological Synthesis of Difunctional Alkanes from Carbohydrate Feedstocks | CELEXION, LLC (US) | 2011-07-14 | — | — | US | disclosed |
| US-20100151536-A1 | Biological Synthesis of Difunctional Alkanes from Carbohydrate Feedstocks | CELEXION, LLC | 2010-06-17 | — | — | US | disclosed |