SCHEMBL10000423

SCHEMBL10000423

COC(=O)C=C(CC(=O)OC)C(=O)OC

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGAM O43451 1/20 0.41
GAA P10253 1/20 0.41
SI P14410 1/20 0.41
MGAM2 Q2M2H8 1/20 0.41
TET2 Q6N021 1/20 0.39
TSHR P16473 4/20 0.39
HCAR2 Q8TDS4 2/20 0.39
KEAP1 Q14145 1/20 0.39
NFE2L2 Q16236 1/20 0.39
HSD17B10 Q99714 1/20 0.36
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
POLB P06746 1/20 0.32
POLA1 P09884 1/20 0.32
ALDH1A1 P00352 2/20 0.31
TP53 P04637 1/20 0.31
LMNA P02545 1/20 0.31
EGLN1 Q9GZT9 1/20 0.30
FNTA P49354 1/20 0.30
FNTB P49356 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12332891 1.00 MGAM (0.41) MGAMGAASIMGAM2TET2
SCHEMBL9910358 0.83 TSHR (0.52) MGAMGAASIMGAM2TET2
SCHEMBL27627561 0.83 TSHR (0.52) MGAMGAASIMGAM2TET2
SCHEMBL4449636 0.83 KEAP1 (0.32) HCAR2KEAP1NFE2L2ALDH1A1LMNA
SCHEMBL31563652 0.83 TSHR (0.41) MGAMGAASIMGAM2TET2
SCHEMBL19087933 0.83 TSHR (0.41) MGAMGAASIMGAM2TET2
SCHEMBL31362035 0.83 TSHR (0.41) MGAMGAASIMGAM2TET2
SCHEMBL280474 0.80 TSHR (0.56) TET2TSHRHCAR2KEAP1NFE2L2
SCHEMBL7774759 0.80 HCAR2 (0.40) TET2HCAR2KEAP1NFE2L2ALDH1A1
SCHEMBL10430503 0.80 HCAR2 (0.40) TET2HCAR2KEAP1NFE2L2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101479818-A Additive for electrolyte and electrolyte OTSUKA CHEMICAL CO LTD (JP) 2009-07-08 CN claimed
CN-119281383-A Mesoporous silica catalyst for catalyzing esterification reaction of tricarboxylic acid, and preparation method and application thereof 中国科学院青岛生物能源与过程研究所 2025-01-10 CN disclosed
CN-109124826-B Ophthalmic lens 爱博诺德(北京)医疗科技股份有限公司 2025-01-10 CN disclosed
CN-118994808-A PVC composite material with high cold resistance and preparation method and application thereof 中国科学院青岛生物能源与过程研究所 2024-11-22 CN disclosed
WO-2024235233-A1 BIO-BASED TRANS-ACONITATE, PREPARATION METHOD THEREFOR AND USE THEREOF 中国科学院青岛生物能源与过程研究所 2024-11-21 WO disclosed
US-12076888-B2 Stabilized compositions and process for producing same CYTEC INDUSTRIES INC. (US) 2024-09-03 US disclosed
US-11925686-B2 Materials for phototherapies of ophthalmic diseases EYEBRIGHT MEDICAL TECHNOLOGY (BEIJING) CO., LTD. (CN) 2024-03-12 US disclosed
CN-115627027-A Encapsulated stabilizer composition 塞特工业公司 2023-01-20 CN disclosed
US-20220048218-A1 STABILIZED COMPOSITIONS AND PROCESS FOR PRODUCING SAME CYTEC INDUSTRIES INC. (US) 2022-02-17 US disclosed
US-9481643-B2 Fluorosurfactants MERCK PATENT GMBH (DE) 2016-11-01 US disclosed
US-20150246875-A1 FLUOROSURFACTANTS MERCK PATENT GMBH (DE) 2015-09-03 US disclosed
US-9115062-B2 Fluorosurfactants MERCK PATENT GMBH (DE) 2015-08-25 US disclosed
US-20120111233-A1 FLUOROSURFACTANTS MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2012-05-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150246875-A1 FLUOROSURFACTANTS FPR3, Q6ZSR9, FLNB MGAM 799/4885GAA 949/4885SI 3088/4885
US-20120111233-A1 FLUOROSURFACTANTS Q6ZSR9, PFAS, FPR3 MGAM 523/4885GAA 612/4885SI 1909/4885
US-11925686-B2 Materials for phototherapies of ophthalmic diseases ALDH1A2, LCP1, PDE6C MGAM 220/4885GAA 266/4885SI 2961/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.