Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | MGAM | O43451 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SI | P14410 | 1/20 | 0.33 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27627561 | 1.00 | TSHR (0.52) | TSHRKMT2AMEN1LMNAKDM4E | |
| SCHEMBL280474 | 0.89 | TSHR (0.56) | TSHRKMT2AMEN1LMNAKDM4E | |
| SCHEMBL27674025 | 0.84 | TSHR (0.52) | TSHRKMT2AMEN1LMNAKDM4E | |
| SCHEMBL12332891 | 0.83 | MGAM (0.41) | TSHRKMT2AMEN1LMNAALDH1A1 | |
| SCHEMBL10000423 | 0.83 | MGAM (0.41) | TSHRKMT2AMEN1LMNAALDH1A1 | |
| SCHEMBL7772525 | 0.82 | HCAR2 (0.37) | TSHRALDH1A1KEAP1NFE2L2HCAR2 | |
| SCHEMBL6877098 | 0.82 | HCAR2 (0.37) | TSHRALDH1A1KEAP1NFE2L2HCAR2 | |
| SCHEMBL280330 | 0.81 | TSHR (0.48) | TSHRKMT2AMEN1LMNAKDM4E | |
| SCHEMBL8844392 | 0.80 | HCAR2 (0.36) | TSHRKEAP1NFE2L2HCAR2 | |
| SCHEMBL8844401 | 0.80 | HCAR2 (0.36) | TSHRKEAP1NFE2L2HCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8192976-B2 | Biological synthesis of difunctional alkanes from carbohydrate feedstocks | CELEXION, LLC (US) | 2012-06-05 | — | — | US | disclosed |
| US-20100151536-A1 | Biological Synthesis of Difunctional Alkanes from Carbohydrate Feedstocks | CELEXION, LLC | 2010-06-17 | — | — | US | disclosed |