Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 6/20 | 0.49 |
| ▸ | CA12 | O43570 | 7/20 | 0.45 |
| ▸ | CA1 | P00915 | 7/20 | 0.45 |
| ▸ | CA2 | P00918 | 7/20 | 0.45 |
| ▸ | CA4 | P22748 | 7/20 | 0.45 |
| ▸ | CA7 | P43166 | 7/20 | 0.45 |
| ▸ | CA9 | Q16790 | 7/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1530101 | 0.81 | CYP17A1 (0.48) | HPGDCA12CA1CA2CA4 | |
| SCHEMBL31299076 | 0.80 | HPGD (0.53) | HPGDCA12CA1CA2CA9 | |
| SCHEMBL1530832 | 0.79 | HPGD (0.44) | HPGDCA12CA1CA2CA4 | |
| SCHEMBL16686200 | 0.77 | ALDH1A1 (0.47) | HPGDLMNASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL11124739 | 0.76 | HSP90AA1 (0.42) | HPGDCA12CA1CA2CA4 | |
| SCHEMBL4154530 | 0.76 | HPGD (0.41) | HPGDLMNAHTTSMN1; SMN2AR | |
| SCHEMBL3039450 | 0.73 | NPC1 (0.56) | HPGDHTTSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL16685886 | 0.73 | SMN1; SMN2 (0.49) | HPGDLMNAHTTSMN1; SMN2KDM4E | |
| SCHEMBL6464101 | 0.73 | SAE1 (0.55) | HPGDCA12CA1CA2CA9 | |
| SCHEMBL114997 | 0.72 | MAPT (0.54) | HPGDLMNAHTTSMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102746239-B | Uracil or thymine derivatives for the treatment of hepatitis C | ABBVIE INC. (BS) | 2016-02-10 | — | — | CN | disclosed |