Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | CES2 | O00748 | 1/20 | 0.45 |
| ▸ | CES1 | P23141 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.41 |
| ▸ | MAOA | P21397 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Aniline SCHEMBL21145291 | 0.88 | TSHR (0.55) | TSHRCES2CES1MAPTL3MBTL1 | |
| Aniline SCHEMBL28107374 | 0.86 | TSHR (0.52) | TSHRCES2CES1MAPTL3MBTL1 | |
| Aniline SCHEMBL27866527 | 0.86 | TSHR (0.52) | TSHRCES2CES1MAPTL3MBTL1 | |
| Biphenyl SCHEMBL22558147 | 0.83 | MAPT (0.59) | TSHRCES2CES1MAPTL3MBTL1 | |
| Aniline SCHEMBL27330317 | 0.82 | TSHR (0.61) | TSHRCES2CES1MAPTL3MBTL1 | |
| Aniline SCHEMBL11138449 | 0.82 | TSHR (0.61) | TSHRCES2CES1MAPTL3MBTL1 | |
| Aniline SCHEMBL27917067 | 0.82 | TSHR (0.69) | TSHRCES2CES1MAPTL3MBTL1 | |
| Aniline SCHEMBL11591138 | 0.82 | TSHR (0.69) | TSHRCES2CES1MAPTL3MBTL1 | |
| Benzene SCHEMBL5712631 | 0.82 | FFAR3 (0.50) | TSHRCES2CES1MAPTL3MBTL1 | |
| Toluene SCHEMBL10973065 | 0.81 | LMNA (0.52) | TSHRCES2CES1MAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116406302-A | Method of transglutaminase conjugation with amino acid based linkers | 阿拉里斯生物技术股份公司 | 2023-07-07 | — | — | CN | disclosed |
| CN-116096753-A | Antibodies specific for ABCB5 and uses thereof | 儿童医学中心公司 | 2023-05-09 | — | — | CN | disclosed |
| CN-110249050-A | Without label coding library of compounds | 南纳治疗有限公司 | 2019-09-17 | — | — | CN | disclosed |
| CN-105102480-A | Prolactin receptor binding proteins and uses thereof | ABBVIE INC | 2015-11-25 | — | — | CN | disclosed |