Aniline

Aniline

SCHEMBL28107374

CCC(=O)CC.Nc1ccccc1

nearest known ligand 0.52

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.52
HSD11B1 P28845 1/20 0.48
TDP1 Q9NUW8 3/20 0.48
CES2 O00748 1/20 0.45
CES1 P23141 1/20 0.45
MAPT P10636 2/20 0.42
L3MBTL1 Q9Y468 2/20 0.42
SMN1; SMN2 Q16637 2/20 0.42
PBRM1 Q86U86 1/20 0.42
CYP3A4 P08684 3/20 0.41
CYP1A2 P05177 2/20 0.41
MAOA P21397 2/20 0.41
LMNA P02545 1/20 0.41
RAB9A P51151 2/20 0.40
ALDH1A1 P00352 2/20 0.39
KDM4E B2RXH2 1/20 0.39
CYP2D6 P10635 1/20 0.39
CYP2C9 P11712 1/20 0.39
CYP2C19 P33261 1/20 0.39
MAOB P27338 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Aniline SCHEMBL21145291 0.88 TSHR (0.55) TSHRHSD11B1TDP1CES2CES1
SCHEMBL27852747 0.87 TDP1 (0.56) TSHRTDP1MAPTL3MBTL1CYP3A4
Aniline SCHEMBL27866527 0.86 TSHR (0.52) TSHRHSD11B1TDP1CES2CES1
Aniline SCHEMBL28047459 0.86 TSHR (0.52) TSHRHSD11B1TDP1CES2CES1
SCHEMBL27896486 0.83 SMN1; SMN2 (0.50) TSHRHSD11B1TDP1CES2CES1
Biphenyl SCHEMBL22163814 0.80 MAPT (0.61) TSHRHSD11B1TDP1CES2CES1
Aniline SCHEMBL25370313 0.79 TSHR (0.65) TSHRTDP1CES2CES1MAPT
Aniline SCHEMBL7175507 0.79 TSHR (0.65) TSHRTDP1CES2CES1MAPT
Aniline SCHEMBL1956601 0.79 TSHR (0.65) TSHRTDP1CES2CES1MAPT
Aniline SCHEMBL30678504 0.79 TSHR (0.65) TSHRTDP1CES2CES1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106117113-A Polysubstituted carbazole, derivant and synthetic method thereof 湘潭大学 2016-11-16 CN claimed
CN-109068644-A Insect repellant FMC有限公司 2018-12-21 CN disclosed
CN-108369377-A Radiation-sensitive resin composition, cured film, pattern forming method, solid-state imaging element, and image display device 富士胶片株式会社 2018-08-03 CN disclosed
CN-107205447-A Beverage precursor and the method for preparing beverage 奥驰亚客户服务有限责任公司 2017-09-26 CN disclosed
CN-107141884-A Rabbet ink composition for electroplating printed circuit board through hole 深圳中富电路有限公司 2017-09-08 CN disclosed