Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | FADS1 | O60427 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.46 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.45 |
| ▸ | AURKA | O14965 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27929422 | 0.82 | AURKB (0.51) | MEN1KMT2ANPC1RAB9AAURKB | |
| SCHEMBL31424193 | 0.82 | MEN1 (0.72) | MEN1KMT2AALDH1A1L3MBTL1FADS1 | |
| SCHEMBL259352 | 0.82 | MEN1 (0.72) | MEN1KMT2AALDH1A1L3MBTL1FADS1 | |
| SCHEMBL392794 | 0.80 | ALDH1A1 (0.59) | MEN1KMT2AALDH1A1FADS1PTGS1 | |
| SCHEMBL12491782 | 0.78 | MEN1 (0.66) | MEN1KMT2AALDH1A1FADS1PTGS1 | |
| Hydrochloric Acid SCHEMBL11743648 | 0.78 | ALDH1A1 (0.58) | MEN1KMT2AALDH1A1FADS1PTGS1 | |
| SCHEMBL27758310 | 0.78 | CYP1A2 (0.62) | KMT2AALDH1A1FADS1SMN1; SMN2NPC1 | |
| SCHEMBL28471669 | 0.77 | FADS1 (0.63) | MEN1KMT2AALDH1A1L3MBTL1FADS1 | |
| SCHEMBL29029890 | 0.76 | ALDH1A1 (0.64) | MEN1KMT2AALDH1A1FADS1PTGS1 | |
| SCHEMBL27826357 | 0.76 | NPC1 (0.61) | MEN1KMT2AALDH1A1FADS1PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103435562-B | 6-replaces Benzodiazepine-2,4-cyclohexadione compounds and uses thereof | EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2016-02-24 | — | — | CN | disclosed |