Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 1/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.57 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.57 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | NAMPT | P43490 | 1/20 | 0.54 |
| ▸ | TNKS | O95271 | 1/20 | 0.54 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.51 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.51 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.51 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL192484 | 1.00 | PLAU (0.64) | PLAUL3MBTL1HDAC1HDAC3HDAC2 | |
| Benzyl Benzylcarbamate SCHEMBL1136818 | 0.90 | PLAU (0.70) | PLAUHDAC1HDAC3HDAC2SMN1; SMN2 | |
| Benzyl Benzylcarbamate SCHEMBL9998166 | 0.89 | PLAU (0.68) | PLAUHDAC1HDAC3HDAC2SMN1; SMN2 | |
| Benzyl Benzylcarbamate SCHEMBL19810513 | 0.89 | PLAU (0.68) | PLAUHDAC1HDAC3HDAC2SMN1; SMN2 | |
| Benzyl Benzylcarbamate SCHEMBL28413454 | 0.89 | PLAU (0.68) | PLAUHDAC1HDAC3HDAC2SMN1; SMN2 | |
| SCHEMBL191161 | 0.87 | PLAU (0.68) | PLAUL3MBTL1HDAC1HDAC3HDAC2 | |
| SCHEMBL20047179 | 0.86 | PLAU (0.66) | PLAUL3MBTL1HDAC1HDAC3HDAC2 | |
| Benzyl Benzylcarbamate SCHEMBL29011837 | 0.85 | PLAU (0.65) | PLAUHDAC1HDAC3HDAC2SMN1; SMN2 | |
| SCHEMBL20022975 | 0.85 | L3MBTL1 (0.57) | PLAUL3MBTL1SMN1; SMN2HPGDMAPT | |
| SCHEMBL5943754 | 0.85 | GLA (0.56) | PLAUL3MBTL1HDAC1HDAC3HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109071560-B | Thienopyridine carboxamides as ubiquitin-specific protease inhibitors | 瓦洛健康公司 | 2022-01-14 | — | — | CN | disclosed |
| CN-105209450-A | Molecules and intermediates having pesticidal utility, compositions and methods relating thereto | DOW AGROSCIENCES LLC | 2015-12-30 | — | — | CN | disclosed |