Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.49 |
| ▸ | MME | P08473 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.44 |
| ▸ | CD274 | Q9NZQ7 | 3/20 | 0.44 |
| ▸ | ACE | P12821 | 1/20 | 0.44 |
| ▸ | CPA1 | P15085 | 1/20 | 0.44 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28047681 | 1.00 | PTPN1 (0.49) | PTPN1MMEALDH1A1ALOX15FOLH1 | |
| SCHEMBL28047718 | 0.90 | PTPN1 (0.61) | PTPN1ALDH1A1ALOX15CD274 | |
| SCHEMBL28047720 | 0.90 | PTPN1 (0.61) | PTPN1ALDH1A1ALOX15CD274 | |
| SCHEMBL28047692 | 0.84 | PTPN1 (0.60) | PTPN1ALDH1A1ALOX15 | |
| SCHEMBL28047694 | 0.84 | PTPN1 (0.60) | PTPN1ALDH1A1ALOX15 | |
| SCHEMBL28047785 | 0.80 | CD274 (0.55) | PTPN1CD274 | |
| SCHEMBL28047787 | 0.80 | CD274 (0.55) | PTPN1CD274 | |
| SCHEMBL28047714 | 0.79 | PTPN1 (0.49) | PTPN1CD274 | |
| SCHEMBL28047709 | 0.79 | PTPN1 (0.49) | PTPN1CD274 | |
| 1,3,5-Trimethoxybenzene SCHEMBL27988490 | 0.79 | FOLH1 (0.50) | MMEFOLH1ACECPA1ACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105189446-A | Phloroglucinol derivatives and application thereof in treatment of neurodegenerative disorder | INST MATERIA MEDICA CAMS | 2015-12-23 | — | — | CN | claimed |
| CN-105189446-A | Phloroglucinol derivatives and application thereof in treatment of neurodegenerative disorder | INST MATERIA MEDICA CAMS | 2015-12-23 | — | — | CN | disclosed |