Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | FPR2 | P25090 | 2/20 | 0.51 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.50 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | CD274 | Q9NZQ7 | 4/20 | 0.47 |
| ▸ | PDCD1 | Q15116 | 2/20 | 0.47 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28047720 | 1.00 | PTPN1 (0.61) | PTPN1ALDH1A1ALOX15GAAFPR2 | |
| SCHEMBL28047694 | 0.91 | PTPN1 (0.60) | PTPN1ALDH1A1ALOX15ITGA4ITGB7 | |
| SCHEMBL28047692 | 0.91 | PTPN1 (0.60) | PTPN1ALDH1A1ALOX15ITGA4ITGB7 | |
| SCHEMBL28047681 | 0.90 | PTPN1 (0.49) | PTPN1ALDH1A1ALOX15CD274 | |
| SCHEMBL28047686 | 0.90 | PTPN1 (0.49) | PTPN1ALDH1A1ALOX15CD274 | |
| SCHEMBL28047785 | 0.82 | CD274 (0.55) | PTPN1CD274PDCD1 | |
| SCHEMBL28047787 | 0.82 | CD274 (0.55) | PTPN1CD274PDCD1 | |
| SCHEMBL11374004 | 0.81 | ALDH1A1 (0.50) | ALDH1A1ALOX15GAAFPR2ITGA4 | |
| SCHEMBL29228692 | 0.81 | FPR2 (0.62) | ALDH1A1ALOX15FPR2KMT2A | |
| SCHEMBL30872672 | 0.81 | FPR2 (0.62) | ALDH1A1ALOX15FPR2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105189446-A | Phloroglucinol derivatives and application thereof in treatment of neurodegenerative disorder | INST MATERIA MEDICA CAMS | 2015-12-23 | — | — | CN | claimed |
| CN-105189446-A | Phloroglucinol derivatives and application thereof in treatment of neurodegenerative disorder | INST MATERIA MEDICA CAMS | 2015-12-23 | — | — | CN | disclosed |