Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.60 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.55 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.55 |
| ▸ | ATM | Q13315 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28047694 | 1.00 | PTPN1 (0.60) | PTPN1ITGA4ITGB7ATMPOLB | |
| SCHEMBL28047720 | 0.91 | PTPN1 (0.61) | PTPN1ITGA4ITGB7CAPN1ALDH1A1 | |
| SCHEMBL28047718 | 0.91 | PTPN1 (0.61) | PTPN1ITGA4ITGB7CAPN1ALDH1A1 | |
| SCHEMBL28047681 | 0.84 | PTPN1 (0.49) | PTPN1ALDH1A1ALOX15 | |
| SCHEMBL28047686 | 0.84 | PTPN1 (0.49) | PTPN1ALDH1A1ALOX15 | |
| SCHEMBL28047857 | 0.81 | PTPN1 (0.47) | PTPN1 | |
| SCHEMBL28047858 | 0.81 | PTPN1 (0.47) | PTPN1 | |
| SCHEMBL3959739 | 0.81 | ATM (0.68) | ITGA4ITGB7ATMPOLBALDH1A1 | |
| SCHEMBL2375644 | 0.81 | ATM (0.68) | ITGA4ITGB7ATMPOLBALDH1A1 | |
| SCHEMBL2375646 | 0.81 | ATM (0.68) | ITGA4ITGB7ATMPOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105189446-A | Phloroglucinol derivatives and application thereof in treatment of neurodegenerative disorder | INST MATERIA MEDICA CAMS | 2015-12-23 | — | — | CN | disclosed |