SCHEMBL28047745

SCHEMBL28047745

C[N+](C)(C)CCOC(=O)CCCC(=O)O

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADRA2A P08913 1/20 0.69
ADRA1A P35348 1/20 0.69
MAPT P10636 1/20 0.67
BLM P54132 1/20 0.67
CYP2C19 P33261 2/20 0.53
CHRM1 P11229 7/20 0.52
CHRM3 P20309 7/20 0.52
CHRM5 P08912 6/20 0.52
CHRM2 P08172 6/20 0.52
CHRM4 P08173 6/20 0.52
CHRNB2 P17787 4/20 0.52
CHRNA4 P43681 4/20 0.52
CHRNA7 P36544 3/20 0.52
TSHR P16473 2/20 0.52
HTR1A P08908 2/20 0.52
SMN1; SMN2 Q16637 2/20 0.52
PGR P06401 1/20 0.52
TBXA2R P21731 1/20 0.52
CHRNB4 P30926 1/20 0.52
CHRNA3 P32297 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25408257 0.96 ADRA2A (0.69) ADRA2AADRA1AMAPTBLMCYP2C19
SCHEMBL8087679 0.94 ADRA2A (0.67) ADRA2AADRA1AMAPTBLMCYP2C19
Choline SCHEMBL25406334 0.93 ADRA2A (0.60) ADRA2AADRA1AMAPTBLMCYP2C19
SCHEMBL16353041 0.92 ADRA2A (0.82) ADRA2AADRA1AMAPTBLMCYP2C19
SCHEMBL3037579 0.88 ADRA2A (0.83) ADRA2AADRA1AMAPTBLMCYP2C19
SCHEMBL16353067 0.87 ADRA2A (0.82) ADRA2AADRA1AMAPTBLMCYP2C19
Hydrochloric Acid SCHEMBL25376349 0.86 MAPT (0.83) ADRA2AADRA1AMAPTBLMCYP2C19
SCHEMBL1984572 0.85 ADRA2A (0.78) ADRA2AADRA1AMAPTBLMCYP2C19
SCHEMBL8087675 0.85 ADRA2A (0.78) ADRA2AADRA1AMAPTBLMCYP2C19
SCHEMBL12560596 0.84 ADRA2A (0.69) ADRA2AADRA1AMAPTBLMCYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105315164-A Environment-friendly choline ionic liquid and preparation method therefor DALIAN CHEMICAL PHYSICS INST 2016-02-10 CN disclosed