Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 known ✓ | P11229 | 8/20 | 0.57 |
| ▸ | CHRM3 known ✓ | P20309 | 8/20 | 0.57 |
| ▸ | CHRM2 known ✓ | P08172 | 7/20 | 0.55 |
| ▸ | ACHE known ✓ | P22303 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.83 |
| ▸ | BLM | P54132 | 1/20 | 0.83 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.79 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.79 |
| ▸ | CHRM5 | P08912 | 6/20 | 0.57 |
| ▸ | CHRM4 | P08173 | 7/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.55 |
| ▸ | CHRNB2 | P17787 | 4/20 | 0.54 |
| ▸ | CHRNA4 | P43681 | 4/20 | 0.54 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.54 |
| ▸ | HTR1A | P08908 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | PGR | P06401 | 1/20 | 0.54 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.54 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.54 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3037579 | 0.98 | ADRA2A (0.83) | MAPTBLMADRA2AADRA1ACHRM1 | |
| Hydrochloric Acid SCHEMBL27500997 | 0.94 | ADRA2A (0.76) | MAPTBLMADRA2AADRA1ACHRM1 | |
| Suxamethonium SCHEMBL41536 | 0.91 | MAPT (1.00) | MAPTBLMADRA2AADRA1ACHRM1 | |
| Suxamethonium SCHEMBL20815392 | 0.89 | MAPT (0.95) | MAPTBLMADRA2AADRA1ACHRM1 | |
| Suxamethonium SCHEMBL1983256 | 0.89 | MAPT (0.95) | MAPTBLMADRA2AADRA1ACHRM1 | |
| Suxamethonium SCHEMBL41537 | 0.89 | ADRA2A (1.00) | MAPTBLMADRA2AADRA1ACHRM1 | |
| Suxamethonium SCHEMBL1643328 | 0.87 | ADRA2A (0.95) | MAPTBLMADRA2AADRA1ACHRM1 | |
| Suxamethonium SCHEMBL21356923 | 0.87 | ADRA2A (0.95) | MAPTBLMADRA2AADRA1ACHRM1 | |
| Suxamethonium SCHEMBL2821312 | 0.87 | ADRA2A (0.95) | MAPTBLMADRA2AADRA1ACHRM1 | |
| Suxamethonium SCHEMBL2690356 | 0.87 | ADRA2A (0.95) | MAPTBLMADRA2AADRA1ACHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106518618-A | Method for continuously extracting, rectificating and separating isopropanol-isopropyl ether azeotrope by mixed solvent | 济南大学 | 2017-03-22 | — | — | CN | claimed |
| US-20230248837-A1 | Technology for Modulating Targeting Chimeras Induced by Cell-Penetrating Peptide and Application Thereof | LIU, MIAO (CN) | 2023-08-10 | — | — | US | disclosed |
| CN-106518618-A | Method for continuously extracting, rectificating and separating isopropanol-isopropyl ether azeotrope by mixed solvent | 济南大学 | 2017-03-22 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230248837-A1 | Technology for Modulating Targeting Chimeras Induced by Cell-Penetrating Peptide and Application Thereof | VIP, GHITM, MYCBP | CHRM1 3666/4885CHRM3 2221/4885CHRM2 3303/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.