Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | MPO | P05164 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.42 |
| ▸ | MAOB | P27338 | 3/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 2/20 | 0.41 |
| ▸ | AGXT | P21549 | 2/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.40 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
| ▸ | MGMT | P16455 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28000659 | 0.78 | NPC1 (0.47) | L3MBTL1NPC1RAB9AMPOTAAR1 | |
| SCHEMBL27697197 | 0.76 | CYP19A1 (0.49) | RAB9A | |
| SCHEMBL28003702 | 0.76 | NPC1 (0.42) | L3MBTL1NPC1RAB9AMPOTAAR1 | |
| SCHEMBL28816893 | 0.76 | NPC1 (0.50) | L3MBTL1NPC1RAB9AMPOTAAR1 | |
| SCHEMBL29520054 | 0.74 | CHRNA7 (0.44) | MPO | |
| SCHEMBL29442856 | 0.74 | MAP4K4 (0.45) | L3MBTL1NPC1RAB9AMPOTAAR1 | |
| SCHEMBL21384071 | 0.74 | MAP4K4 (0.45) | L3MBTL1NPC1RAB9AMPOTAAR1 | |
| SCHEMBL1774870 | 0.74 | DHFR (0.69) | — | |
| SCHEMBL3121450 | 0.73 | HTR2C (0.42) | L3MBTL1NPC1TAAR1MAOBHTR2C | |
| SCHEMBL15537208 | 0.72 | MAP4K4 (0.60) | TLR8TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105189481-A | Pyridine cdk9 kinase inhibitors | ABBVIE INC | 2015-12-23 | — | — | CN | disclosed |