Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | MC4R | P32245 | 1/20 | 0.53 |
| ▸ | CHKA | P35790 | 5/20 | 0.49 |
| ▸ | PRMT6 | Q96LA8 | 2/20 | 0.49 |
| ▸ | NCF1 | P14598 | 2/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | PARP1 | P09874 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL547278 | 0.89 | LMNA (0.66) | LMNAMC4RCHKAPRMT6NCF1 | |
| SCHEMBL13535291 | 0.83 | MC4R (0.74) | LMNAMC4RCHKAPRMT6NCF1 | |
| SCHEMBL29715963 | 0.79 | LMNA (0.64) | LMNAMC4RCHKAPRMT6NCF1 | |
| SCHEMBL469049 | 0.79 | PRMT6 (0.72) | LMNAMC4RCHKAPRMT6NCF1 | |
| SCHEMBL62758 | 0.79 | LMNA (0.64) | LMNAMC4RCHKAPRMT6NCF1 | |
| SCHEMBL16178546 | 0.77 | LMNA (0.62) | LMNAMC4RCHKAPRMT6NCF1 | |
| Hydrochloric Acid SCHEMBL1675838 | 0.77 | LMNA (0.62) | LMNAMC4RCHKAPRMT6NCF1 | |
| Hydrochloric Acid SCHEMBL14999805 | 0.77 | LMNA (0.62) | LMNAMC4RCHKAPRMT6NCF1 | |
| SCHEMBL22169184 | 0.77 | LMNA (0.62) | LMNAMC4RCHKAPRMT6NCF1 | |
| Hydrochloric Acid SCHEMBL3974793 | 0.77 | LMNA (0.62) | LMNAMC4RCHKAPRMT6NCF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105189481-A | Pyridine cdk9 kinase inhibitors | ABBVIE INC | 2015-12-23 | — | — | CN | disclosed |