Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | GMNN | O75496 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | FYN | P06241 | 1/20 | 0.40 |
| ▸ | CA3 | P07451 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydantoin SCHEMBL27362965 | 0.84 | TDP1 (0.44) | KDM4EMAPTL3MBTL1ALDH1A1TDP1 | |
| 2-Phenylphenol SCHEMBL8682334 | 0.83 | ALDH1A1 (0.55) | L3MBTL1ALDH1A1RAB9AHPGDALOX15 | |
| Hydantoin SCHEMBL27574136 | 0.80 | CRBN (0.46) | MAPTL3MBTL1ALDH1A1TDP1CA12 | |
| Hydantoin SCHEMBL9422302 | 0.80 | — | — | |
| Hydantoin SCHEMBL5011714 | 0.80 | — | — | |
| Biphenyl SCHEMBL1712625 | 0.79 | TYRO3 (0.42) | KDM4EALDH1A1LMNAMMP9HPGD | |
| Hydantoin SCHEMBL27916388 | 0.79 | TRPA1 (0.55) | KDM4EMAPTL3MBTL1ALDH1A1POLB | |
| Biphenyl SCHEMBL9013643 | 0.78 | TYRO3 (0.41) | KDM4EALDH1A1LMNAMMP9HPGD | |
| Hydantoin SCHEMBL27690 | 0.78 | — | — | |
| Hydantoin SCHEMBL27705088 | 0.78 | CRBN (0.52) | MAPTL3MBTL1ALDH1A1TDP1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1924734-B1 | METHOD FOR ATTACHMENT OF SILICON-CONTAINING COMPOUNDS TO A SURFACE AND FOR THE SYNTHESIS OF HYPERVALENT SILICON-COMPOUNDS | ALEXIUM INC (US) | 2017-01-04 | — | — | EP | disclosed |
| US-20120128930-A1 | Method for Attachment of Silicon-Containing Compounds to a Surface and for Synthesis of Hypervalent Silicon-Compounds | UNITED STATES AIR FORCE | 2012-05-24 | — | — | US | disclosed |
| US-20100239784-A1 | Method for attachment of silicon-containing compounds to a surface and for synthesis of hypervalent silicon-compounds | ALEXIUM, INC. | 2010-09-23 | — | — | US | disclosed |
| EP-1924734-A1 | METHOD FOR ATTACHMENT OF SILICON-CONTAINING COMPOUNDS TO A SURFACE AND FOR THE SYNTHESIS OF HYPERVALENT SILICON-COMPOUNDS | Alexium Limited (CY) | 2008-05-28 | — | — | EP | disclosed |
| WO-2007031775-A1 | METHOD FOR ATTACHMENT OF SILICON-CONTAINING COMPOUNDS TO A SURFACE AND FOR THE SYNTHESIS OF HYPERVALENT SILICON-COMPOUNDS | ALEXIUM LIMITED (CY) | 2007-03-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120128930-A1 | Method for Attachment of Silicon-Containing Compounds to a Surface and for Synthesis of Hypervalent Silicon-Compounds | VCL, PDS5B, PDS5A | KDM4E 2824/4885MAPT 1502/4885L3MBTL1 2712/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.