Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.35 |
| ▸ | HTR3B | O95264 | 1/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.35 |
| ▸ | HTR3A | P46098 | 1/20 | 0.35 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.35 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | GSK3A | P49840 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL4203457 | 0.98 | HTR3E (0.34) | HTR3EHTR3BADRB1HTR3AHTR3D | |
| SCHEMBL4272763 | 0.84 | LMNA (0.42) | HTR3EHTR3BADRB1HTR3AHTR3D | |
| Hydrochloric Acid SCHEMBL3940286 | 0.82 | LMNA (0.40) | HTR3EHTR3BADRB1HTR3AHTR3D | |
| Iodide SCHEMBL2530875 | 0.81 | — | — | |
| SCHEMBL666883 | 0.78 | MAPT (0.37) | SIGMAR1MAPTGSK3AGSK3BMEN1 | |
| Iodide SCHEMBL28360230 | 0.77 | MAPT (0.36) | SIGMAR1MAPTGSK3AGSK3BMEN1 | |
| SCHEMBL11442754 | 0.77 | GAA (0.42) | MAPTGAALMNATDP1 | |
| Hydrochloric Acid SCHEMBL384463 | 0.77 | MAPT (0.36) | SIGMAR1MAPTGSK3AGSK3BMEN1 | |
| Iodide SCHEMBL3820109 | 0.77 | MAPT (0.36) | SIGMAR1MAPTGSK3AGSK3BMEN1 | |
| SCHEMBL14675935 | 0.76 | KDM4E (0.42) | MAPTKDM4ELMNAALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105189506-A | Compounds and compositions for the treatment of parasitic diseases | NOVARTIS AG | 2015-12-23 | — | — | CN | disclosed |