Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 10/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | DHFR | P00374 | 1/20 | 0.46 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | STAT1 | P42224 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | NT5E | P21589 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28046862 | 0.89 | AURKA (0.45) | DHODHGAAALDH1A1MAPTKDM4E | |
| SCHEMBL7610953 | 0.83 | GRM2 (0.58) | ALDH1A1MAPTKDM4EKMT2APOLB | |
| SCHEMBL14409758 | 0.83 | ALDH1A1 (0.65) | DHODHGAAALDH1A1MAPTKDM4E | |
| SCHEMBL30064613 | 0.83 | ALDH1A1 (0.65) | DHODHGAAALDH1A1MAPTKDM4E | |
| SCHEMBL28349800 | 0.83 | DHODH (0.61) | DHODHGAAALDH1A1MAPTKDM4E | |
| SCHEMBL1104820 | 0.80 | CYP1A2 (0.62) | ALDH1A1MAPTKDM4ENPSR1POLB | |
| SCHEMBL11827110 | 0.80 | MAPK1 (0.47) | DHODHALDH1A1MAPTKDM4EMEN1 | |
| SCHEMBL28883104 | 0.80 | MAPK1 (0.61) | DHODHGAAALDH1A1MAPTKDM4E | |
| Iodide SCHEMBL30847747 | 0.79 | CYP1A2 (0.60) | ALDH1A1MAPTKDM4ENPSR1POLB | |
| SCHEMBL23267810 | 0.79 | ALDH1A1 (0.46) | GAAALDH1A1MAPTKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105198806-A | Method for synthesizing quinoline by aromatic amine and diketone | UNIV NANYANG NORMAL | 2015-12-30 | — | — | CN | disclosed |
| CN-105175327-A | Synthesis method of quinoline derivatives | UNIV NANYANG NORMAL | 2015-12-23 | — | — | CN | disclosed |