Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.61 |
| ▸ | AURKA | O14965 | 1/20 | 0.59 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.59 |
| ▸ | ELANE | P08246 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.50 |
| ▸ | FABP3 | P05413 | 1/20 | 0.50 |
| ▸ | FABP4 | P15090 | 1/20 | 0.50 |
| ▸ | MAT2A | P31153 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.48 |
| ▸ | DHODH | Q02127 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28046810 | 0.89 | POLB (0.60) | MAPK1AURKAAURKBELANEKDM4E | |
| SCHEMBL14409758 | 0.83 | ALDH1A1 (0.65) | MAPK1KDM4ELMNAL3MBTL1DHODH | |
| SCHEMBL30064613 | 0.83 | ALDH1A1 (0.65) | MAPK1KDM4ELMNAL3MBTL1DHODH | |
| SCHEMBL8956330 | 0.83 | MAPK1 (0.85) | MAPK1AURKAAURKBELANEKDM4E | |
| SCHEMBL11826284 | 0.83 | MAPK1 (0.65) | MAPK1AURKAAURKBELANEKDM4E | |
| SCHEMBL28883096 | 0.82 | LMNA (0.60) | MAPK1AURKAAURKBKDM4ELMNA | |
| SCHEMBL7770732 | 0.81 | AURKA (0.73) | MAPK1AURKAAURKBELANEKDM4E | |
| SCHEMBL8410911 | 0.81 | MAPK1 (0.82) | MAPK1AURKAAURKBELANEKDM4E | |
| SCHEMBL1104820 | 0.80 | CYP1A2 (0.62) | KDM4EPOLBMAPTALDH1A1HPGD | |
| SCHEMBL497480 | 0.80 | MAPK1 (0.61) | MAPK1AURKAAURKBELANEKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110092751-B | Synthesis method of 2-alkyl quinoline | 安徽工程大学宣城产业技术研究院有限公司 | 2022-11-11 | — | — | CN | disclosed |