SCHEMBL28048341

SCHEMBL28048341

CCC(OC(C)=O)(C(=O)O)c1cccc(C(=O)c2ccccc2)c1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.45
ATM Q13315 1/20 0.45
TDP1 Q9NUW8 1/20 0.45
SRD5A2 P31213 1/20 0.43
LMNA P02545 2/20 0.42
MAPK1 P28482 2/20 0.42
ELANE P08246 2/20 0.42
PBRM1 Q86U86 1/20 0.40
PTGS1 P23219 3/20 0.38
PTGS2 P35354 3/20 0.38
MAPT P10636 2/20 0.38
CXCR1 P25024 2/20 0.38
CXCR2 P25025 2/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
ALDH1A1 P00352 2/20 0.38
RECQL P46063 1/20 0.38
KDM4E B2RXH2 1/20 0.38
CYP3A4 P08684 1/20 0.38
HPGD P15428 1/20 0.38
PMP22 Q01453 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11483165 0.79 L3MBTL1 (0.42) L3MBTL1ATMTDP1SRD5A2LMNA
SCHEMBL15547074 0.76 L3MBTL1 (0.52) L3MBTL1ATMTDP1SRD5A2LMNA
SCHEMBL11732389 0.74 MEN1 (0.54) L3MBTL1ATMTDP1SRD5A2LMNA
SCHEMBL17710486 0.73 L3MBTL1 (0.45) L3MBTL1ATMTDP1SRD5A2LMNA
SCHEMBL11482204 0.73 ATM (0.45) L3MBTL1ATMTDP1SRD5A2LMNA
SCHEMBL11483157 0.73 L3MBTL1 (0.41) L3MBTL1ATMTDP1SRD5A2ELANE
SCHEMBL7488968 0.71 ATM (0.59) L3MBTL1ATMTDP1SRD5A2LMNA
SCHEMBL30238332 0.71 L3MBTL1 (0.59) L3MBTL1ATMTDP1SRD5A2LMNA
SCHEMBL3684740 0.71 ATM (0.63) L3MBTL1ATMTDP1SRD5A2LMNA
SCHEMBL11301851 0.70 L3MBTL1 (0.49) L3MBTL1ATMTDP1SRD5A2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105339340-A Base generator, base-reactive composition containing said base generator, and base generation method WAKO PURE CHEM IND LTD 2016-02-17 CN disclosed