SCHEMBL17710486

SCHEMBL17710486

CC(=O)OCC(C)(C(=O)O)c1cccc(C(=O)c2ccccc2)c1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.45
ATM Q13315 1/20 0.45
TDP1 Q9NUW8 1/20 0.45
SRD5A2 P31213 1/20 0.43
ELANE P08246 5/20 0.42
PTGS1 P23219 3/20 0.41
PTGS2 P35354 3/20 0.41
KIF11 P52732 1/20 0.40
PBRM1 Q86U86 1/20 0.40
VNN1 O95497 1/20 0.39
PPARA Q07869 1/20 0.39
MAPT P10636 2/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
CXCR1 P25024 1/20 0.38
CXCR2 P25025 1/20 0.38
RECQL P46063 1/20 0.38
ACHE P22303 1/20 0.38
KDM4E B2RXH2 1/20 0.38
ALDH1A1 P00352 1/20 0.38
LMNA P02545 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15547074 0.81 L3MBTL1 (0.52) L3MBTL1ATMTDP1SRD5A2PTGS1
SCHEMBL11483161 0.81 L3MBTL1 (0.41) L3MBTL1ATMTDP1SRD5A2ELANE
SCHEMBL17710567 0.80 L3MBTL1 (0.50) L3MBTL1ATMTDP1SRD5A2PTGS1
SCHEMBL17710499 0.80 L3MBTL1 (0.50) L3MBTL1ATMTDP1SRD5A2PTGS1
SCHEMBL17710582 0.80 L3MBTL1 (0.50) L3MBTL1ATMTDP1SRD5A2PTGS1
SCHEMBL20373860 0.79 L3MBTL1 (0.49) L3MBTL1ATMTDP1SRD5A2PTGS1
SCHEMBL30238332 0.75 L3MBTL1 (0.59) L3MBTL1ATMTDP1SRD5A2ELANE
SCHEMBL7488968 0.75 ATM (0.59) L3MBTL1ATMTDP1SRD5A2ELANE
SCHEMBL3684740 0.74 ATM (0.63) L3MBTL1ATMTDP1SRD5A2PTGS1
SCHEMBL11301851 0.73 L3MBTL1 (0.49) L3MBTL1ATMTDP1SRD5A2PTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3018118-B1 BASE GENERATOR, BASE-REACTIVE COMPOSITION CONTAINING SAID BASE GENERATOR, AND BASE GENERATION METHOD FUJIFILM WAKO PURE CHEMICAL CORP (JP) 2023-07-05 EP disclosed
US-10428014-B2 Base generator, base-reactive composition containing said base generator, and base generation method FUJIFILM WAKO PURE CHEMICAL CORPORATION (JP) 2019-10-01 US disclosed
EP-3018118-A1 BASE GENERATOR, BASE-REACTIVE COMPOSITION CONTAINING SAID BASE GENERATOR, AND BASE GENERATION METHOD Wako Pure Chemical Industries, Ltd. (JP) 2016-05-11 EP disclosed
US-20160122292-A1 BASE GENERATOR, BASE-REACTIVE COMPOSITION CONTAINING SAID BASE GENERATOR, AND BASE GENERATION METHOD TOKYO UNIVERSITY OF SCIENCE FOUNDATION (JP) 2016-05-05 US disclosed
CN-105339340-A Base generator, base-reactive composition containing said base generator, and base generation method WAKO PURE CHEM IND LTD 2016-02-17 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10428014-B2 Base generator, base-reactive composition containing said base generator, and base generation method HPRT1, GNG2, BLM L3MBTL1 4682/4885ATM 2369/4885TDP1 774/4885
US-20160122292-A1 BASE GENERATOR, BASE-REACTIVE COMPOSITION CONTAINING SAID BASE GENERATOR, AND BASE GENERATION METHOD GNG2, EPHX2, ARHGEF1 L3MBTL1 3859/4885ATM 3371/4885TDP1 1991/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.