Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 3/20 | 0.46 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.46 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | APOBEC3A | P31941 | 2/20 | 0.41 |
| ▸ | APOBEC3G | Q9HC16 | 2/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | PRCP | P42785 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25348323 | 0.98 | OPRM1 (0.45) | OPRM1OPRD1OPRK1AKR1C1DRD3 | |
| SCHEMBL24944034 | 0.85 | OPRM1 (0.48) | OPRM1OPRD1OPRK1DRD3 | |
| SCHEMBL26939253 | 0.85 | OPRM1 (0.45) | OPRM1OPRD1OPRK1AKR1C1DRD3 | |
| SCHEMBL28391947 | 0.83 | OPRM1 (0.44) | OPRM1OPRD1OPRK1AKR1C1DRD3 | |
| SCHEMBL22790441 | 0.83 | OPRM1 (0.60) | OPRM1OPRD1OPRK1AKR1C1DRD3 | |
| SCHEMBL23637639 | 0.83 | OPRM1 (0.44) | OPRM1OPRD1OPRK1AKR1C1DRD3 | |
| SCHEMBL26939254 | 0.83 | HDAC4 (0.45) | OPRM1OPRD1OPRK1AKR1C1DRD3 | |
| SCHEMBL6036843 | 0.82 | AKR1C1 (0.52) | OPRM1OPRD1OPRK1AKR1C1SMN1; SMN2 | |
| SCHEMBL9191673 | 0.80 | AKR1C1 (0.50) | OPRM1AKR1C1SMN1; SMN2HDAC4MEN1 | |
| SCHEMBL9191670 | 0.80 | AKR1C1 (0.50) | AKR1C1SMN1; SMN2HDAC4MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103284974-B | Benzene ring nonyl ester double-layer osmotic pump controlled-release tablet and preparation method thereof | WUHAN GENERAL HOSPITAL OF GUANGZHOU MILITARY COMMAND, PLA (CN) | 2016-01-20 | — | — | CN | disclosed |