Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.57 |
| ▸ | PI4KA | P42356 | 5/20 | 0.44 |
| ▸ | PI4K2B | Q8TCG2 | 5/20 | 0.44 |
| ▸ | PI4K2A | Q9BTU6 | 5/20 | 0.44 |
| ▸ | PI4KB | Q9UBF8 | 5/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | XDH | P47989 | 1/20 | 0.44 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.40 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.39 |
| ▸ | EIF4E | P06730 | 1/20 | 0.38 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.38 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.38 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.38 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL397656 | 0.98 | DYRK1A (0.59) | DYRK1API4KAPI4K2BPI4K2API4KB | |
| Hydrochloric Acid SCHEMBL3353317 | 0.96 | DYRK1A (0.57) | DYRK1API4KAPI4K2BPI4K2API4KB | |
| Formic Acid SCHEMBL31745015 | 0.87 | DYRK1A (0.49) | DYRK1API4KAPI4K2BPI4K2API4KB | |
| SCHEMBL1056424 | 0.72 | DYRK1A (0.59) | DYRK1AEIF4EMKNK1MKNK2IRAK4 | |
| SCHEMBL8223 | 0.72 | DYRK1A (1.00) | DYRK1AEIF4EMKNK1MKNK2IRAK4 | |
| SCHEMBL23158613 | 0.72 | DYRK1A (0.64) | DYRK1AEIF4EMKNK1MKNK2IRAK4 | |
| SCHEMBL3386908 | 0.72 | DYRK1A (0.59) | DYRK1AMAP4K4EIF4EMKNK1MKNK2 | |
| SCHEMBL32425027 | 0.72 | DYRK1A (1.00) | DYRK1AEIF4EMKNK1MKNK2IRAK4 | |
| SCHEMBL2078428 | 0.72 | DYRK1A (0.59) | DYRK1AEIF4EMKNK1MKNK2IRAK4 | |
| SCHEMBL13186164 | 0.72 | DYRK1A (0.59) | DYRK1AEIF4EMKNK1MKNK2IRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105367576-A | Pyrrolopyrimidine compounds as TLR7 agonists | CHIA TAI TIANQING PHARMACEUTICAL GROUP CO LTD | 2016-03-02 | — | — | CN | disclosed |