Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.49 |
| ▸ | PI4K2A | Q9BTU6 | 6/20 | 0.42 |
| ▸ | PI4KA | P42356 | 4/20 | 0.42 |
| ▸ | PI4K2B | Q8TCG2 | 4/20 | 0.42 |
| ▸ | PI4KB | Q9UBF8 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | XDH | P47989 | 1/20 | 0.42 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.38 |
| ▸ | EIF4E | P06730 | 1/20 | 0.35 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.35 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.35 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.34 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.34 |
| ▸ | AKT1 | P31749 | 1/20 | 0.33 |
| ▸ | NUDT1 | P36639 | 2/20 | 0.33 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29702869 | 0.89 | DYRK1A (0.59) | DYRK1API4K2API4KAPI4K2BPI4KB | |
| SCHEMBL397656 | 0.89 | DYRK1A (0.59) | DYRK1API4K2API4KAPI4K2BPI4KB | |
| Hydrochloric Acid SCHEMBL3353317 | 0.87 | DYRK1A (0.57) | DYRK1API4K2API4KAPI4K2BPI4KB | |
| SCHEMBL28048489 | 0.87 | DYRK1A (0.57) | DYRK1API4K2API4KAPI4K2BPI4KB | |
| Formic Acid SCHEMBL31744986 | 0.76 | PTPN11 (0.40) | DYRK1AAKT1 | |
| SCHEMBL27691640 | 0.74 | DYRK1A (0.55) | DYRK1AEIF4EMKNK1MKNK2IRAK4 | |
| SCHEMBL14087078 | 0.71 | DYRK1A (0.47) | DYRK1AEIF4EMKNK1MKNK2IRAK4 | |
| SCHEMBL29494927 | 0.70 | DYRK1A (0.50) | DYRK1API4K2API4KBMKNK1IRAK4 | |
| SCHEMBL1056424 | 0.70 | DYRK1A (0.59) | DYRK1AEIF4EMKNK1MKNK2IRAK4 | |
| SCHEMBL14074733 | 0.68 | DYRK1A (0.52) | DYRK1AEIF4EMKNK1MKNK2IRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250382305-A1 | COMPOUNDS FOR TREATING SPINOCEREBELLAR ATAXIA TYPE 3 | PTC THERAPEUTICS INC (US) | 2025-12-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250382305-A1 | COMPOUNDS FOR TREATING SPINOCEREBELLAR ATAXIA TYPE 3 | ATXN2, SMN1; SMN2, ATXN10 | DYRK1A 3549/4885PI4K2A 2840/4885PI4KA 3622/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.