Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.64 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.49 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.49 |
| ▸ | LTA4H | P09960 | 4/20 | 0.49 |
| ▸ | PTGIR | P43119 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18713086 | 0.87 | LTA4H (0.54) | HRH3KCNH2LTA4HKDM4E | |
| SCHEMBL23944117 | 0.86 | HRH3 (0.49) | HRH3KCNH2LTA4H | |
| SCHEMBL23179559 | 0.86 | HRH3 (0.49) | HRH3KCNH2MCHR1CYP2D6KDM4E | |
| SCHEMBL15483888 | 0.84 | KDM4E (0.50) | HRH3KCNH2MCHR1KDM4EPOLB | |
| SCHEMBL22812069 | 0.83 | HRH3 (0.47) | HRH3KCNH2MCHR1LTA4H | |
| SCHEMBL23179756 | 0.83 | HRH3 (0.47) | HRH3KCNH2MCHR1LTA4HCYP2D6 | |
| SCHEMBL18705095 | 0.83 | HRH3 (0.52) | HRH3KCNH2LTA4HKDM4ETSHR | |
| SCHEMBL23126249 | 0.82 | HRH3 (0.46) | HRH3KCNH2MCHR1LTA4H | |
| SCHEMBL13004104 | 0.81 | HRH3 (0.62) | HRH3KCNH2LTA4HCYP2D6TSHR | |
| SCHEMBL23972277 | 0.81 | HRH3 (0.58) | HRH3LTA4HCYP2D6MAOAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105367576-A | Pyrrolopyrimidine compounds as TLR7 agonists | CHIA TAI TIANQING PHARMACEUTICAL GROUP CO LTD | 2016-03-02 | — | — | CN | disclosed |