SCHEMBL28048598

SCHEMBL28048598

COCOCCOS(=O)(=O)C(F)(F)F

nearest known ligand 0.37

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CA2 P00918 3/20 0.37
CA1 P00915 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18856639 0.86 CA2 (0.40) CA2CA1
SCHEMBL1759185 0.83 CA2 (0.41) CA2CA1
SCHEMBL4949681 0.83 CA2 (0.43) CA2CA1
SCHEMBL4953881 0.83 CA2 (0.43) CA2CA1
SCHEMBL4949086 0.83 CA2 (0.43) CA2CA1
Methoxymethane SCHEMBL8159900 0.82 CA2 (0.38) CA2CA1
SCHEMBL29094937 0.81 CA2 (0.40) CA2CA1
Ammonia Solution, Strong SCHEMBL28134013 0.81 CA2 (0.40) CA2CA1
SCHEMBL3132111 0.81 CA2 (0.36) CA2CA1
SCHEMBL1032931 0.80 CA2 (0.47) CA2CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114539288-B Preparation method of everolimus 鲁南制药集团股份有限公司 2024-01-30 CN disclosed
CN-114539288-A Efficient everolimus preparation method 鲁南制药集团股份有限公司 2022-05-27 CN disclosed
CN-105254646-A Everolimus preparation method SHANGHAI BIOBOND PHARMACEUTICAL CO LTD 2016-01-20 CN disclosed