Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.50 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.50 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19707956 | 0.87 | PDE4A (0.51) | KMT2AATMMEN1RAB9ANPSR1 | |
| SCHEMBL1416792 | 0.85 | KMT2A (0.55) | KMT2AMEN1RAB9ALMNASMN1; SMN2 | |
| SCHEMBL14518781 | 0.84 | PDE4D (0.52) | KMT2AATMMEN1RAB9ANPSR1 | |
| SCHEMBL29440418 | 0.83 | GSK3B (0.53) | KMT2AATMMEN1RAB9ANPSR1 | |
| SCHEMBL1542192 | 0.83 | GSK3B (0.53) | KMT2AATMMEN1RAB9ANPSR1 | |
| SCHEMBL13780117 | 0.82 | KAT6A (0.52) | MRGPRX4 | |
| SCHEMBL2277217 | 0.81 | KMT2A (0.54) | KMT2AATMMEN1RAB9ANPSR1 | |
| SCHEMBL733307 | 0.81 | CES2 (0.67) | KMT2AMEN1RAB9AMAPTLMNA | |
| SCHEMBL25736079 | 0.81 | ERCC5 (0.49) | KMT2ARAB9AMAPTSMN1; SMN2GAA | |
| SCHEMBL10883891 | 0.81 | HDAC3 (0.60) | KMT2AATMMEN1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104411709-B | Can be used as imidazo [2, the 1] thiazole-3-ketone derivatives of the diagnostic agent of Alzheimer | 霍夫曼-拉罗奇有限公司 | 2016-08-24 | — | — | CN | disclosed |
| CN-102844318-B | Be used for the treatment of the compound of respiratory syncytial virus infection | BIOTA SCIENTIFIC MANAGEMENT PTY LTD. (AU) | 2016-04-13 | — | — | CN | disclosed |
| CN-103906746-B | (4-phenylimidazol-2-yl) ethylamine derivatives as sodium channel modulators | PFIZER LTD. (GB) | 2015-12-09 | — | — | CN | disclosed |