Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 11/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | RXRA | P19793 | 1/20 | 0.43 |
| ▸ | RXRB | P28702 | 1/20 | 0.43 |
| ▸ | RXRG | P48443 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.43 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | SYK | P43405 | 1/20 | 0.42 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.42 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28821202 | 0.88 | MRGPRX4 (0.46) | MRGPRX4RXRARXRBRXRGCREBBP | |
| SCHEMBL28024479 | 0.88 | HIF1A (0.43) | MRGPRX4CYP2C9HIF1ARXRARXRB | |
| SCHEMBL27877447 | 0.83 | MRGPRX4 (0.59) | MRGPRX4RXRARXRBRXRGFOLH1 | |
| SCHEMBL28024050 | 0.80 | MRGPRX4 (0.46) | MRGPRX4CYP2C9HIF1ARXRARXRB | |
| SCHEMBL28825558 | 0.80 | MRGPRX4 (0.44) | MRGPRX4CYP2C9HIF1ARXRARXRB | |
| SCHEMBL28049551 | 0.79 | NR4A2 (0.50) | MRGPRX4MAOBALDH1A1RXFP1 | |
| SCHEMBL28024517 | 0.79 | MRGPRX4 (0.38) | MRGPRX4CYP2C9HIF1ARXRARXRB | |
| SCHEMBL28024548 | 0.78 | MRGPRX4 (0.43) | MRGPRX4RXRARXRBRXRG | |
| SCHEMBL28024063 | 0.78 | MRGPRX4 (0.43) | MRGPRX4CYP2C9HIF1ARXRARXRB | |
| SCHEMBL28954513 | 0.78 | CYP2C9 (0.43) | MRGPRX4CYP2C9HIF1ARXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105263921-A | Tetrazolinone compound and application of same | SUMITOMO CHEMICAL CO | 2016-01-20 | — | — | CN | disclosed |