Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 10/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | RXRA | P19793 | 1/20 | 0.35 |
| ▸ | RXRB | P28702 | 1/20 | 0.35 |
| ▸ | RXRG | P48443 | 1/20 | 0.35 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.35 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28821025 | 0.88 | FFAR1 (0.39) | MRGPRX4FFAR1FFAR4 | |
| SCHEMBL28024067 | 0.83 | WDR5 (0.38) | MRGPRX4 | |
| SCHEMBL28048671 | 0.79 | MRGPRX4 (0.46) | MRGPRX4CYP2C9HIF1ARXRARXRB | |
| SCHEMBL28024479 | 0.74 | HIF1A (0.43) | MRGPRX4LMNACYP2C9HIF1ARXRA | |
| SCHEMBL27877447 | 0.72 | MRGPRX4 (0.59) | MRGPRX4RXRARXRBRXRGFOLH1 | |
| SCHEMBL28825558 | 0.71 | MRGPRX4 (0.44) | MRGPRX4CYP2C9HIF1ARXRARXRB | |
| SCHEMBL28048667 | 0.71 | MRGPRX4 (0.40) | MRGPRX4LMNACD274 | |
| SCHEMBL28049551 | 0.70 | NR4A2 (0.50) | MRGPRX4FFAR1FFAR4 | |
| SCHEMBL28024050 | 0.69 | MRGPRX4 (0.46) | MRGPRX4LMNACYP2C9HIF1ARXRA | |
| SCHEMBL28024548 | 0.69 | MRGPRX4 (0.43) | MRGPRX4RXRARXRBRXRG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104884442-A | Tetrazolinone compound and applications thereof | SUMITOMO CHEMICAL CO | 2015-09-02 | — | — | CN | disclosed |