Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 1/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.48 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.46 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.46 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.46 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.45 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.45 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4363303 | 0.80 | FFAR1 (0.56) | SLC6A4KDM4EADRA2AADRA2BADRA2C | |
| SCHEMBL4946642 | 0.79 | CHRNB2 (0.51) | SMN1; SMN2CHRNB4CHRNA3CHRNB2CHRNA4 | |
| SCHEMBL29854164 | 0.79 | CHRNB2 (0.51) | SMN1; SMN2CHRNB4CHRNA3CHRNB2CHRNA4 | |
| SCHEMBL9423384 | 0.79 | CFTR (0.48) | CFTRSLC6A2SLC6A4SLC6A3GOPC | |
| SCHEMBL4671890 | 0.79 | CFTR (0.48) | CFTRSLC6A2SLC6A4SLC6A3GOPC | |
| SCHEMBL6904351 | 0.76 | FFAR1 (0.61) | KDM4EADRA2AADRA2BADRA2CPOLB | |
| SCHEMBL28037256 | 0.76 | CHRNB2 (0.49) | CHRNB4CHRNA3CHRNB2CHRNA4HTT | |
| SCHEMBL1515202 | 0.76 | CHRNB2 (0.49) | CHRNB4CHRNA3CHRNB2CHRNA4HTT | |
| SCHEMBL14477064 | 0.76 | CHRNB2 (0.49) | SMN1; SMN2CHRNB4CHRNA3CHRNB2CHRNA4 | |
| SCHEMBL2485031 | 0.76 | CHRNB2 (0.49) | CHRNB4CHRNA3CHRNB2CHRNA4HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105189515-A | Furopyridines as bromodomain inhibitors | GLAXOSMITHKLINE IP NO 2 LTD | 2015-12-23 | — | — | CN | disclosed |