Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | DRD4 | P21917 | 1/20 | 0.45 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.45 |
| ▸ | PARP1 | P09874 | 1/20 | 0.45 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.45 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.42 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.42 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.42 |
| ▸ | PNMT | P11086 | 1/20 | 0.41 |
| ▸ | CD44 | P16070 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Indoline SCHEMBL29360339 | 0.93 | — | — | |
| Indoline SCHEMBL5629 | 0.93 | — | — | |
| Indoline SCHEMBL17746180 | 0.91 | PARP10 (0.50) | HTR2CDRD2DRD4PDPK1PARP1 | |
| Indoline SCHEMBL10723456 | 0.91 | HTR2C (0.50) | HTR2CDRD2DRD4PDPK1PARP1 | |
| Indoline SCHEMBL4903255 | 0.91 | HTR2C (0.50) | HTR2CDRD2DRD4PDPK1PARP1 | |
| Indoline SCHEMBL23295083 | 0.91 | HTR2C (0.50) | HTR2CDRD2DRD4PDPK1PARP1 | |
| Indoline SCHEMBL6872936 | 0.91 | HTR2C (0.50) | HTR2CDRD2DRD4PDPK1PARP1 | |
| Indoline SCHEMBL8194348 | 0.91 | HTR2C (0.50) | HTR2CDRD2DRD4PDPK1PARP1 | |
| Indoline SCHEMBL1085136 | 0.91 | HTR2C (0.50) | HTR2CDRD2DRD4PDPK1PARP1 | |
| Indoline SCHEMBL8297160 | 0.91 | HTR2C (0.50) | HTR2CDRD2DRD4PDPK1PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105153011-A | Synthesis method of 2-sulfonyliminoindoline | UNIV CHANGZHOU | 2015-12-16 | — | — | CN | claimed |
| CN-105153011-B | A kind of synthetic method of 2- sulfimides indoline | 常州大学 | 2018-06-26 | — | — | CN | disclosed |
| CN-105153011-A | Synthesis method of 2-sulfonyliminoindoline | UNIV CHANGZHOU | 2015-12-16 | — | — | CN | disclosed |