Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 9/20 | 0.50 |
| ▸ | NPC1 | O15118 | 9/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4557665 | 0.77 | RAB9A (0.58) | RAB9ANPC1SMN1; SMN2CYP1A2KMT2A | |
| SCHEMBL25346779 | 0.76 | RAB9A (0.62) | RAB9ANPC1ALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL11410257 | 0.75 | NPC1 (0.57) | RAB9ANPC1ALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL1269767 | 0.75 | RAB9A (0.60) | RAB9ANPC1ALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL2773834 | 0.75 | SMN1; SMN2 (0.64) | RAB9ANPC1ALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL28015608 | 0.74 | NPC1 (0.49) | RAB9ANPC1ALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL1181120 | 0.74 | RAB9A (0.52) | RAB9ANPC1ALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL1684582 | 0.73 | HPGD (0.57) | RAB9ANPC1ALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL12317134 | 0.71 | KMT2A (0.59) | RAB9ANPC1ALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL3923726 | 0.71 | RAB9A (0.56) | RAB9ANPC1ALDH1A1MAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102858768-B | Substituted triazolopyridines | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-01-20 | — | — | CN | disclosed |