SCHEMBL8557428

SCHEMBL8557428

C=C(C)OC(=O)CC(N)C(=O)O

nearest known ligand 0.50

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
GRIK1 P39086 12/20 0.50
GRIK2 Q13002 7/20 0.50
GRM1 Q13255 1/20 0.50
GRM2 Q14416 1/20 0.50
GRIA4 P48058 3/20 0.44
GRIK3 Q13003 3/20 0.44
GRIK5 Q16478 3/20 0.44
SLC7A5 Q01650 1/20 0.43
SLC1A1 P43005 4/20 0.40
SLC1A3 P43003 4/20 0.39
SLC1A2 P43004 4/20 0.39
HSD17B10 Q99714 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
GRIA2 P42262 2/20 0.39
GRIA1 P42261 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14177513 0.86 HSD17B10 (0.41) GRIK1GRIK2GRM1GRM2HSD17B10
SCHEMBL7781249 0.83 GRIK1 (0.50) GRIK1GRIK2GRM1GRM2GRIA4
Acetic Acid SCHEMBL27618718 0.82 GRIK1 (0.48) GRIK1GRIK2GRM1GRM2GRIA4
SCHEMBL12399215 0.81 SLC1A1 (0.50) GRIK1GRIK2GRM1GRM2GRIA4
SCHEMBL27399004 0.79 GRIK1 (0.46) GRIK1GRIK2GRM1GRM2GRIA4
SCHEMBL28048940 0.78 GRIK1 (0.46) GRIK1GRIK2GRM1GRM2GRIA4
SCHEMBL28204942 0.77 GRIK1 (0.45) GRIK1GRIK2GRM1GRM2GRIA4
SCHEMBL28296240 0.77 GRIK1 (0.45) GRIK1GRIK2GRM1GRM2GRIA4
SCHEMBL27955347 0.77 GRIK1 (0.45) GRIK1GRIK2GRM1GRM2GRIA4
SCHEMBL27401897 0.77 GRIK1 (0.45) GRIK1GRIK2GRM1GRM2GRIA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5739093-A DETERGENT CONTAINING ETHYLENE APARTIC GLUTAMIC ACID OR SALT THEREOF; IMPROVED STAIN REMOVAL LEVER BROTHERS COMPANY, DIVISION OF CONOPCO, INC. (US) 1998-04-14 US disclosed
US-5688996-A DETERGENTS OR BUILDERS LEVER BROTHERS COMPANY, DIVISION OF CONOPCO, INC. (US) 1997-11-18 US disclosed
EP-0796842-A2 Ethylene aspartate cysteate sequestrants, methods of producing them and detergent compositions containing them UNILEVER PLC (GB) 1997-09-24 EP disclosed
US-5668098-A Detergent compositions containing ethylene aspartate cysteate (EAC) sequestrants LEVER BROTHERS COMPANY, DIVISION OF CONOPCO, INC. (US) 1997-09-16 US disclosed