Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 4/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.44 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.44 |
| ▸ | CPN1 | P15169 | 1/20 | 0.39 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TACR1 | P25103 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2206877 | 0.87 | HIF1A (0.47) | ADRB3ADRB2ADRB1POLBRAB9A | |
| SCHEMBL27785071 | 0.86 | NPC1 (0.39) | POLBNPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL28682475 | 0.86 | POLB (0.40) | ADRB3ADRB2ADRB1POLBNPC1 | |
| SCHEMBL28673428 | 0.85 | POLB (0.50) | ADRB3ADRB2ADRB1POLBNPC1 | |
| SCHEMBL611538 | 0.83 | NPC1 (0.41) | ADRB3ADRB2ADRB1POLBNPC1 | |
| SCHEMBL15809658 | 0.79 | POLB (0.55) | ADRB3ADRB2ADRB1POLBNPC1 | |
| SCHEMBL15809660 | 0.79 | POLB (0.55) | ADRB3ADRB2ADRB1POLBNPC1 | |
| SCHEMBL27953236 | 0.77 | MAPT (0.43) | POLBL3MBTL1MAPTAOC3 | |
| SCHEMBL27787225 | 0.77 | MAOA (0.42) | ADRB3ADRB2ADRB1TACR1L3MBTL1 | |
| SCHEMBL27995424 | 0.77 | ADRB2 (0.41) | ADRB3ADRB2ADRB1CPN1CPB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105209428-A | Substituted 3-phenylpropylamine derivatives for the treatment of ophthalmic diseases and disorders | ACUCELA INC | 2015-12-30 | — | — | CN | disclosed |