Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 8/20 | 0.53 |
| ▸ | KIT | P10721 | 6/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | DHODH | Q02127 | 1/20 | 0.41 |
| ▸ | VNN1 | O95497 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | F11 | P03951 | 1/20 | 0.40 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL185939 | 0.95 | FLT3 (0.49) | FLT3KITRAB9ACYP1A2CYP2D6 | |
| SCHEMBL186306 | 0.88 | RAB9A (0.46) | FLT3KITRAB9ACYP1A2CYP2D6 | |
| SCHEMBL185950 | 0.88 | FLT3 (0.55) | FLT3KITKMT2AMAPK10VNN1 | |
| Hydrochloric Acid SCHEMBL2805862 | 0.86 | FLT3 (0.54) | FLT3KITKMT2AMAPK10VNN1 | |
| SCHEMBL2780905 | 0.82 | FLT3 (0.57) | FLT3KITKMT2AMAPK10PTK2 | |
| Trifluoroacetic Acid SCHEMBL185821 | 0.81 | FLT3 (0.49) | FLT3KITKMT2AMAPK10VNN1 | |
| Trifluoroacetic Acid SCHEMBL2807127 | 0.81 | FLT3 (0.49) | FLT3KITKMT2AMAPK10VNN1 | |
| SCHEMBL2811620 | 0.81 | RAB9A (0.39) | FLT3KITRAB9ACYP1A2CYP2D6 | |
| SCHEMBL14856502 | 0.81 | RAB9A (0.39) | FLT3KITRAB9ACYP1A2CYP2D6 | |
| SCHEMBL2811623 | 0.81 | RAB9A (0.39) | FLT3KITRAB9ACYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130131075-A1 | NEW COMPOUNDS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2013-05-23 | — | — | US | disclosed |
| US-20100240669-A1 | NEW COMPOUNDS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-09-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130131075-A1 | NEW COMPOUNDS | ADORA1, H1-10, P2RY11 | FLT3 632/4885KIT 989/4885RAB9A 347/4885 |
| US-20100240669-A1 | NEW COMPOUNDS | ADORA1, H1-10, P2RY11 | FLT3 632/4885KIT 989/4885RAB9A 347/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.