Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 known ✓ | Q12809 | 1/20 | 0.56 |
| ▸ | FABP3 | P05413 | 6/20 | 0.62 |
| ▸ | TERT | O14746 | 3/20 | 0.56 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.56 |
| ▸ | PPARG | P37231 | 3/20 | 0.56 |
| ▸ | PPARD | Q03181 | 3/20 | 0.56 |
| ▸ | PPARA | Q07869 | 3/20 | 0.56 |
| ▸ | FAAH | O00519 | 3/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.56 |
| ▸ | BLM | P54132 | 2/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | FABP4 | P15090 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | GMNN | O75496 | 1/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphoric Acid SCHEMBL28049093 | 0.93 | FABP3 (0.62) | FABP3TERTPTPN1PPARGPPARD | |
| SCHEMBL4047249 | 0.93 | FABP3 (0.65) | FABP3TERTPTPN1PPARGPPARD | |
| SCHEMBL27509400 | 0.93 | FABP3 (0.65) | FABP3TERTPTPN1PPARGPPARD | |
| SCHEMBL157762 | 0.93 | FABP3 (0.65) | FABP3TERTPTPN1PPARGPPARD | |
| Bromide SCHEMBL23798635 | 0.91 | FABP3 (0.62) | FABP3TERTPTPN1PPARGPPARD | |
| Iodide SCHEMBL9324294 | 0.91 | FABP3 (0.62) | FABP3TERTPTPN1PPARGPPARD | |
| Hydrochloric Acid SCHEMBL1029165 | 0.91 | FABP3 (0.62) | FABP3TERTPTPN1PPARGPPARD | |
| Hydrochloric Acid SCHEMBL6940059 | 0.91 | FABP3 (0.62) | FABP3TERTPTPN1PPARGPPARD | |
| Fluoride Ion SCHEMBL29227705 | 0.91 | FABP3 (0.62) | FABP3TERTPTPN1PPARGPPARD | |
| Water SCHEMBL8017014 | 0.91 | FABP3 (0.62) | FABP3TERTPTPN1PPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105163762-A | Treatment for exposure to nerve agent | UNIV GEORGETOWN | 2015-12-16 | — | — | CN | claimed |
| CN-109312341-A | micro-RNAs and methods of use thereof | 美国政府(由卫生和人类服务部的部长所代表) | 2019-02-05 | — | — | CN | disclosed |
| CN-105163762-A | Treatment for exposure to nerve agent | UNIV GEORGETOWN | 2015-12-16 | — | — | CN | disclosed |