Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.61 |
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.61 |
| ▸ | FABP3 | P05413 | 6/20 | 0.62 |
| ▸ | TERT | O14746 | 3/20 | 0.61 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.61 |
| ▸ | PPARG | P37231 | 3/20 | 0.61 |
| ▸ | PPARD | Q03181 | 3/20 | 0.61 |
| ▸ | PPARA | Q07869 | 3/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.61 |
| ▸ | BLM | P54132 | 2/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.61 |
| ▸ | FABP4 | P15090 | 2/20 | 0.61 |
| ▸ | FAAH | O00519 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | F7 | P08709 | 2/20 | 0.61 |
| ▸ | F3 | P13726 | 2/20 | 0.61 |
| ▸ | GMNN | O75496 | 1/20 | 0.61 |
| ▸ | USP2 | O75604 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL313868 | 1.00 | FABP3 (0.62) | FABP3TERTPTPN1PPARGPPARD | |
| Hydrochloric Acid SCHEMBL27615748 | 1.00 | FABP3 (0.62) | FABP3TERTPTPN1PPARGPPARD | |
| Hydrochloric Acid SCHEMBL1029165 | 1.00 | FABP3 (0.62) | FABP3TERTPTPN1PPARGPPARD | |
| Propane SCHEMBL28471858 | 0.98 | FABP3 (0.61) | FABP3TERTPTPN1PPARGPPARD | |
| Propane SCHEMBL25204223 | 0.98 | FABP3 (0.61) | FABP3TERTPTPN1PPARGPPARD | |
| SCHEMBL27509400 | 0.98 | FABP3 (0.65) | FABP3TERTPTPN1PPARGPPARD | |
| SCHEMBL4047249 | 0.98 | FABP3 (0.65) | FABP3TERTPTPN1PPARGPPARD | |
| SCHEMBL157762 | 0.98 | FABP3 (0.65) | FABP3TERTPTPN1PPARGPPARD | |
| Iodide SCHEMBL9324294 | 0.96 | FABP3 (0.62) | FABP3TERTPTPN1PPARGPPARD | |
| Bromide SCHEMBL4655150 | 0.96 | FABP3 (0.62) | FABP3TERTPTPN1PPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1430498-A | Rinse-off cosmetic conditioning compositions | UNILEVER NV (NL) | 2003-07-16 | — | — | CN | claimed |
| EP-1280497-A2 | RINSE-OFF COSMETIC CONDITIONING COMPOSITIONS | UNILEVER PLC (GB) | 2003-02-05 | — | — | EP | claimed |
| US-20020015685-A1 | Enhanced deposition of hair and skin benefit agents from water-in-oil-in-water conditioner compositions | UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. | 2002-02-07 | — | — | US | claimed |
| WO-2001085108-A2 | RINSE-OFF COSMETIC CONDITIONING COMPOSITIONS | UNILEVER PLC (GB) | 2001-11-15 | — | — | WO | claimed |
| WO-2023157209-A1 | QUANTUM-DOT-CONTAINING COMPOSITION, LIGHT-EMITTING ELEMENT, DISPLAY DEVICE, AND METHOD FOR MANUFACTURING QUANTUM-DOT-CONTAINING COMPOSITION | シャープディスプレイテクノロジー株式会社 | 2023-08-24 | — | — | WO | disclosed |
| EP-3501488-B1 | AQUEOUS SILICONE POLYMER COMPOSITIONS | MOMENTIVE PERFORMANCE MAT GMBH (DE) | 2021-04-14 | — | — | EP | disclosed |
| US-10947383-B2 | Aqueous silicone polymer compositions | MOMENTIVE PERFORMANCE MATERIALS GMBH (DE) | 2021-03-16 | — | — | US | disclosed |
| CN-111718716-A | Nanostructures with inorganic ligands for electroluminescent devices | 纳米系统公司 | 2020-09-29 | — | — | CN | disclosed |
| US-20190194457-A1 | AQUEOUS SILICONE POLYMER COMPOSITIONS | MOMENTIVE PERFORMANCE MATERIALS GMBH (DE) | 2019-06-27 | — | — | US | disclosed |
| EP-3501488-A1 | AQUEOUS SILICONE POLYMER COMPOSITIONS | Momentive Performance Materials GmbH (DE) | 2019-06-26 | — | — | EP | disclosed |
| CN-1430498-A | Rinse-off cosmetic conditioning compositions | UNILEVER NV (NL) | 2003-07-16 | — | — | CN | disclosed |
| CN-1110541-C | Concentrated water-dispersible stable fiber softener compositions | PROCTER & GAMBLE (US) | 2003-06-04 | — | — | CN | disclosed |
| CN-1241205-A | High usage of fabric softener compositions having improved effect | PROCTER & GAMBLE (US) | 2000-01-12 | — | — | CN | disclosed |
| CN-1217038-A | Paper products contg. biodegradable vegetable oil based chemical softening composition | PROCTER & GAMBLE (US) | 1999-05-19 | — | — | CN | disclosed |
| CN-1196081-A | Concentrated, water dispersible, stable, fabric softening compositions | PROCTER & GAMBLE (US) | 1998-10-14 | — | — | CN | disclosed |
| CN-1195369-A | Concentrated and stable fabric softening compositions | PROCTER & GAMBLE (US) | 1998-10-07 | — | — | CN | disclosed |
| CN-1184516-A | Soft creped tissue paper | PROCTER & GAMBLE (US) | 1998-06-10 | — | — | CN | disclosed |
| CN-1174583-A | Soft and creped tissue paper | PROCTER & GAMBLE (US) | 1998-02-25 | — | — | CN | disclosed |
| CN-1163645-A | Paper products containing vegetable oil based chemical softening composition | PROCTER & GAMBLE (US) | 1997-10-29 | — | — | CN | disclosed |
| CN-1128550-A | Waterless self-emulsifiable chemical softening composition useful in fibrous cellulosic materials | PROCTER & GAMBLE (US) | 1996-08-07 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10947383-B2 | Aqueous silicone polymer compositions | CUTA, IL6, SHC1 | CHRM1 2885/4885SLC6A2 4781/4885FABP3 4737/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.