SCHEMBL28049229

SCHEMBL28049229

N#CC(CF)c1cccc(O)c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 6/20 0.53
ESR2 Q92731 6/20 0.53
CCR1 P32246 1/20 0.42
HIF1A Q16665 3/20 0.41
ADRB1 P08588 2/20 0.41
ADRA1A P35348 2/20 0.41
ADRB2 P07550 1/20 0.41
HTR1A P08908 1/20 0.41
ADRA2A P08913 1/20 0.41
ADRB3 P13945 1/20 0.41
TSHR P16473 1/20 0.41
ADRA2B P18089 1/20 0.41
ADRA2C P18825 1/20 0.41
NFKB1 P19838 1/20 0.41
DRD1 P21728 1/20 0.41
HTR7 P34969 1/20 0.41
ADRA1B P35368 1/20 0.41
DRD3 P35462 1/20 0.41
RAB9A P51151 1/20 0.41
SLC6A3 Q01959 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9848442 0.82 ESR1 (0.53) ESR1ESR2CCR1HIF1AADRB1
Hydrochloric Acid SCHEMBL10599419 0.81 ESR1 (0.51) ESR1ESR2CCR1HIF1AADRB1
SCHEMBL7008435 0.79 ESR1 (0.50) ESR1ESR2CCR1HIF1AADRB1
SCHEMBL11019443 0.78 ESR1 (0.56) ESR1ESR2CCR1TSHRSLC6A3
SCHEMBL9256909 0.73 ESR1 (0.59) ESR1ESR2HIF1AADRB1ADRA1A
SCHEMBL3496129 0.73 ESR1 (0.59) ESR1ESR2HIF1AADRB1ADRA1A
SCHEMBL7262478 0.73 ESR1 (0.59) ESR1ESR2HIF1AADRB1ADRA1A
SCHEMBL29818916 0.73 HIF1A (0.54) ESR1ESR2HIF1AADRB1ADRA1A
SCHEMBL17735447 0.73 HIF1A (0.54) ESR1ESR2HIF1AADRB1ADRA1A
SCHEMBL2151108 0.73 HIF1A (0.54) ESR1ESR2HIF1AADRB1ADRA1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105375065-A Electrolyte and lithium ion battery containing same NINGDE AMPEREX TECHNOLOGY LTD 2016-03-02 CN disclosed
CN-105261789-A Electrolyte and lithium ion battery including same NINGDE AMPEREX TECHNOLOGY LTD 2016-01-20 CN disclosed