Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 2/20 | 0.59 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.59 |
| ▸ | TSHR | P16473 | 3/20 | 0.59 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.48 |
| ▸ | MIF | P14174 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
| ▸ | HTR2B | P41595 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.46 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.46 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | DRD1 | P21728 | 1/20 | 0.46 |
| ▸ | HTR7 | P34969 | 1/20 | 0.46 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7262478 | 1.00 | ESR1 (0.59) | ESR1ESR2TSHRADRB1ADRA1A | |
| SCHEMBL3496129 | 1.00 | ESR1 (0.59) | ESR1ESR2TSHRADRB1ADRA1A | |
| SCHEMBL8944137 | 0.79 | ADRB1 (0.48) | ESR1ESR2TSHRADRB1ADRA1A | |
| SCHEMBL6966592 | 0.79 | ADRB1 (0.48) | ESR1ESR2TSHRADRB1ADRA1A | |
| SCHEMBL6691199 | 0.78 | TSHR (0.57) | ESR1ESR2TSHRADRB1ADRB2 | |
| SCHEMBL198178 | 0.78 | TSHR (0.57) | ESR1ESR2TSHRSLC6A3ALDH1A1 | |
| SCHEMBL2162950 | 0.78 | TSHR (0.57) | ESR1ESR2TSHRLMNAALDH1A1 | |
| SCHEMBL21807151 | 0.78 | TSHR (0.57) | ESR1ESR2TSHRHIF1ARAB9A | |
| SCHEMBL7767485 | 0.78 | ESR1 (0.58) | ESR1ESR2TSHRADRB1ADRA1A | |
| SCHEMBL9176673 | 0.78 | TSHR (0.57) | ESR1ESR2TSHRGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0350908-B1 | Process for the production of S-cyanohydrines | FORSCHUNGSZENTRUM JUELICH GMBH (DE) | 1995-06-07 | — | — | EP | disclosed |
| EP-0326063-B1 | Process for the preparation of optically active cyanhydrins | FORSCHUNGSZENTRUM JUELICH GMBH (DE) | 1994-09-07 | — | — | EP | disclosed |
| US-5008192-A | Enzymatic process for the preparation of optically active cyanohydrins | KERNFORSCHUNGSANLAGE JUELICH GMBH (DE) | 1991-04-16 | — | — | US | disclosed |
| EP-0326063-A2 | Process for the preparation of optically active cyanhydrins | FORSCHUNGSZENTRUM JÜLICH GMBH (DE) | 1989-08-02 | — | — | EP | disclosed |