SCHEMBL28049256

SCHEMBL28049256

C[Si](C)(C)Nc1cccc(O)c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 4/20 0.52
TSHR P16473 1/20 0.52
ALDH1A1 P00352 5/20 0.52
CYP1A2 P05177 3/20 0.52
HDAC6 Q9UBN7 1/20 0.52
RAPGEF4 Q8WZA2 1/20 0.48
KMT2A Q03164 5/20 0.47
HSD17B10 Q99714 2/20 0.46
CA12 O43570 1/20 0.46
CA2 P00918 1/20 0.46
LMNA P02545 1/20 0.46
CA5A P35218 1/20 0.46
CA9 Q16790 1/20 0.46
CA14 Q9ULX7 1/20 0.46
CA5B Q9Y2D0 1/20 0.46
MEN1 O00255 3/20 0.44
MAPT P10636 2/20 0.44
USP2 O75604 1/20 0.44
APP P05067 1/20 0.44
HSP90AA1 P07900 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11147093 0.84 MAPT (0.42) CYP3A4TSHRALDH1A1CYP1A2KMT2A
SCHEMBL54893 0.75
SCHEMBL29807871 0.75
SCHEMBL9621766 0.74 MEN1 (0.52) CYP3A4ALDH1A1RAPGEF4KMT2ACA12
SCHEMBL30026816 0.74 CYP3A4 (0.86) CYP3A4TSHRALDH1A1CYP1A2HDAC6
SCHEMBL1389429 0.74 CYP3A4 (0.86) CYP3A4TSHRALDH1A1CYP1A2HDAC6
Bromide SCHEMBL15020875 0.73 CYP3A4 (0.56) CYP3A4TSHRALDH1A1CYP1A2HDAC6
Hydrochloric Acid SCHEMBL22689426 0.73 CYP3A4 (0.56) CYP3A4TSHRALDH1A1CYP1A2HDAC6
SCHEMBL13408236 0.72 ALDH1A1 (0.50) CYP3A4TSHRALDH1A1CYP1A2HDAC6
SCHEMBL13302358 0.72 CYP3A4 (0.82) CYP3A4TSHRALDH1A1CYP1A2HDAC6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105272862-A Preparation method for m-N-ethyl-aminophenol UNIV SHENYANG CHEMICAL TECH 2016-01-27 CN disclosed