SCHEMBL28049301

SCHEMBL28049301

N#Cc1c[c]c(CF)cc1

nearest known ligand 0.37

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
PNMT P11086 3/20 0.36
SIGMAR1 Q99720 2/20 0.36
CYP2A6 P11509 2/20 0.34
LOXL2 Q9Y4K0 2/20 0.34
ALDH1A1 P00352 1/20 0.33
CA12 O43570 1/20 0.33
CA2 P00918 1/20 0.33
CA3 P07451 1/20 0.33
CA6 P23280 1/20 0.33
CA9 Q16790 1/20 0.33
CA14 Q9ULX7 1/20 0.33
KCNJ1 P48048 1/20 0.32
KCNH2 Q12809 1/20 0.32
KIF11 P52732 1/20 0.31
TSHR P16473 1/20 0.31
MMP3 P08254 1/20 0.30
ENPP2 Q13822 1/20 0.30
MAOA P21397 1/20 0.30
MAOB P27338 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL458357 0.79 CYP2A6 (0.48) CYP2A6LOXL2ALDH1A1CA12CA2
SCHEMBL28267186 0.79 LOXL2 (0.48) CYP2A6LOXL2ALDH1A1CA12CA2
SCHEMBL16954973 0.76 CYP2A6 (0.41) CYP2A6LOXL2ALDH1A1KCNJ1KCNH2
SCHEMBL6327803 0.73 TSHR (0.44) CYP2A6ALDH1A1TSHR
SCHEMBL350177 0.71
SCHEMBL623156 0.69 CA2 (0.39) CYP2A6LOXL2ALDH1A1CA12CA2
SCHEMBL6384212 0.68 MAOB (0.49) CYP2A6LOXL2ALDH1A1TSHRMAOA
SCHEMBL351012 0.67
SCHEMBL596317 0.67
SCHEMBL596925 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105261789-B electrolyte and lithium ion battery including the electrolyte 宁德新能源科技有限公司 2018-07-27 CN disclosed
CN-105261789-A Electrolyte and lithium ion battery including same NINGDE AMPEREX TECHNOLOGY LTD 2016-01-20 CN disclosed