Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | RAPGEF4 | Q8WZA2 | 3/20 | 0.36 |
| ▸ | ACHE | P22303 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | SELL | P14151 | 1/20 | 0.33 |
| ▸ | SELP | P16109 | 1/20 | 0.33 |
| ▸ | SELE | P16581 | 1/20 | 0.33 |
| ▸ | TACR1 | P25103 | 2/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | PGR | P06401 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL156099 | 0.96 | — | — | |
| SCHEMBL249769 | 0.89 | — | — | |
| SCHEMBL6291138 | 0.86 | ALDH1A1 (0.48) | ALDH1A1MAPK1TSHRRAPGEF4ACHE | |
| SCHEMBL13232022 | 0.82 | ALDH1A1 (0.40) | ALDH1A1MAPK1TSHRRAPGEF4PGR | |
| SCHEMBL11808958 | 0.80 | ALDH1A1 (0.43) | ALDH1A1MAPK1TSHRRAPGEF4ACHE | |
| SCHEMBL30472802 | 0.80 | ALDH1A1 (0.43) | ALDH1A1MAPK1TSHRRAPGEF4ACHE | |
| Cyanide SCHEMBL28165564 | 0.80 | ALDH1A1 (0.43) | ALDH1A1MAPK1TSHRRAPGEF4ACHE | |
| Fluoride SCHEMBL27303913 | 0.80 | ALDH1A1 (0.39) | ALDH1A1MAPK1RAPGEF4ACHE | |
| SCHEMBL15641762 | 0.78 | ALDH1A1 (0.38) | ALDH1A1MAPK1TSHRRAPGEF4ACHE | |
| SCHEMBL9616495 | 0.78 | IDO1 (0.38) | ALDH1A1MAPK1TSHRTACR1IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105189438-A | Substituted aromatic compounds for treating fibrosis and related methods | PROMETIC BIOSCIENCES INC | 2015-12-23 | — | — | CN | disclosed |