SCHEMBL30472802

SCHEMBL30472802

Cc1cc(Br)cc(-c2cc(C)cc(Br)c2)c1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.43
MAPK1 P28482 1/20 0.43
PGR P06401 1/20 0.42
RXRA P19793 1/20 0.34
RXRB P28702 1/20 0.34
TSHR P16473 3/20 0.33
RAPGEF4 Q8WZA2 2/20 0.33
APEX1 P27695 1/20 0.33
KDM4E B2RXH2 1/20 0.31
MEN1 O00255 1/20 0.31
NPC1 O15118 1/20 0.31
GAA P10253 1/20 0.31
MAPT P10636 1/20 0.31
RAB9A P51151 1/20 0.31
KMT2A Q03164 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
TACR1 P25103 1/20 0.31
CYP3A4 P08684 2/20 0.30
TDP1 Q9NUW8 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11808958 1.00 ALDH1A1 (0.43) ALDH1A1MAPK1PGRRXRARXRB
SCHEMBL13232022 0.94 ALDH1A1 (0.40) ALDH1A1MAPK1PGRRXRARXRB
SCHEMBL15641762 0.91 ALDH1A1 (0.38) ALDH1A1MAPK1PGRRXRARXRB
SCHEMBL13799168 0.85 ALDH1A1 (0.48) ALDH1A1MAPK1PGRRXRARXRB
SCHEMBL30423254 0.85 ALDH1A1 (0.48) ALDH1A1MAPK1PGRRXRARXRB
SCHEMBL156099 0.83
SCHEMBL249769 0.83
SCHEMBL23714949 0.82 NPC1 (0.47) ALDH1A1MAPK1PGRMEN1NPC1
SCHEMBL6291138 0.80 ALDH1A1 (0.48) ALDH1A1MAPK1TSHRRAPGEF4NPSR1
Fluoride SCHEMBL28049696 0.80 ALDH1A1 (0.48) ALDH1A1MAPK1PGRTSHRRAPGEF4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116284143-B Platinum complex and organic electroluminescent device comprising same 季华恒烨(佛山)电子材料有限公司 2024-11-26 CN disclosed
CN-116284143-A Platinum complex and organic electroluminescent device comprising same 季华恒烨(佛山)电子材料有限公司 2023-06-23 CN disclosed