SCHEMBL28049767

SCHEMBL28049767

C=C(CCCC)C(=O)NN(CC)CCC

nearest known ligand 0.34

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CES1 P23141 2/20 0.34
CES2 O00748 1/20 0.34
ALDH1A1 P00352 2/20 0.34
TP53 P04637 1/20 0.32
CA1 P00915 2/20 0.31
FAAH O00519 1/20 0.31
CA12 O43570 1/20 0.31
CA9 Q16790 1/20 0.31
KDM5A P29375 1/20 0.30
KDM4C Q9H3R0 1/20 0.30
DNM1 Q05193 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28049769 0.93 CES1 (0.37) CES1CES2ALDH1A1TP53CA1
SCHEMBL27555245 0.91 CES1 (0.38) CES1CES2ALDH1A1TP53CA1
SCHEMBL28049766 0.89 HDAC3 (0.30) CES1CES2ALDH1A1
SCHEMBL27575116 0.87 CA1 (0.39) CES1CES2ALDH1A1TP53CA1
SCHEMBL28049818 0.82 CA12 (0.34) CES1CES2ALDH1A1CA12CA9
SCHEMBL27628386 0.80 CA12 (0.39) CES1CES2ALDH1A1CA1FAAH
SCHEMBL9180137 0.80 KDM4E (0.34) CES1CES2ALDH1A1
SCHEMBL28049770 0.79 ALDH1A1 (0.41) CES1CES2ALDH1A1TP53CA1
SCHEMBL7644797 0.78 ALDH1A1 (0.43) CES1CES2ALDH1A1TP53CA1
SCHEMBL28049819 0.78 TGFBR1 (0.32) CA12CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102863666-B Rubber composition for tire and pneumatic tyre SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2016-03-02 CN disclosed
CN-103958591-B Rubber composition for tire and pneumatic tyre SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2016-02-03 CN disclosed