Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1171499 | 0.85 | POLB (0.47) | POLBNPSR1LMNATSHRGAA | |
| SCHEMBL18404733 | 0.82 | POLB (0.45) | POLBNPSR1LMNATSHRGAA | |
| SCHEMBL8329339 | 0.80 | LMNA (0.47) | POLBNPSR1LMNATSHRGAA | |
| SCHEMBL28403527 | 0.80 | LMNA (0.47) | POLBNPSR1LMNATSHRGAA | |
| SCHEMBL3134099 | 0.80 | SMN1; SMN2 (0.48) | POLBNPSR1LMNATSHRGAA | |
| SCHEMBL10651815 | 0.79 | LMNA (0.46) | POLBNPSR1LMNATSHRGAA | |
| SCHEMBL8329336 | 0.78 | LMNA (0.44) | POLBNPSR1LMNATSHRGAA | |
| SCHEMBL15631966 | 0.78 | LMNA (0.44) | POLBNPSR1LMNATSHRGAA | |
| Ethyl Acetate SCHEMBL27733464 | 0.78 | CYP1A2 (0.47) | POLBNPSR1LMNATSHRGAA | |
| SCHEMBL25512278 | 0.78 | LMNA (0.44) | POLBNPSR1LMNATSHRGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102718700-B | 3,5,6-tri-Chloro-2-Pyridyle fluoroacetic acid derivative preparations and applicatio is studied | NANKAI UNIVERSITY (CN) | 2016-03-23 | — | — | CN | disclosed |