SCHEMBL28050274

SCHEMBL28050274

CCCCCC1CCC(C(F)(F)Oc2ccc(O)c(F)c2F)CC1

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TRPV1 Q8NER1 1/20 0.33
BCHE P06276 1/20 0.31
ACHE P22303 1/20 0.31
ESR1 P03372 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19891906 0.84 TRPV1 (0.31) TRPV1
SCHEMBL4593881 0.82 ESR1 (0.40) TRPV1BCHEACHEESR1
SCHEMBL4593883 0.82 ESR1 (0.40) TRPV1BCHEACHEESR1
SCHEMBL9562061 0.81 RIPK1 (0.36) TRPV1BCHEACHEESR1
SCHEMBL9562068 0.81 RIPK1 (0.36) TRPV1BCHEACHEESR1
SCHEMBL16979176 0.79 CHRM1 (0.32) ACHE
SCHEMBL17615964 0.78 KDM1A (0.33)
SCHEMBL18079366 0.78 PLA2G2D (0.33)
SCHEMBL14960933 0.77
SCHEMBL14960880 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102591071-B The manufacture method of liquid crystal display cells, liquid crystal display cells and aligning agent for liquid crystal JSR CO., LTD. (JP) 2016-03-16 CN disclosed
CN-102591070-B Liquid crystal display cells and alignment agent JSR CO., LTD. (JP) 2016-02-03 CN disclosed