SCHEMBL4593883

SCHEMBL4593883

CCCCCC1CCC(CCCOc2ccc(O)c(F)c2F)CC1

nearest known ligand 0.40

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 8/20 0.40
CNR2 P34972 2/20 0.36
CNR1 P21554 1/20 0.36
SMPD1 P17405 1/20 0.35
TRPV1 Q8NER1 1/20 0.35
PPARG P37231 1/20 0.35
PTGES O14684 1/20 0.34
ALOX5 P09917 1/20 0.34
BCHE P06276 1/20 0.33
ACHE P22303 1/20 0.33
HPGD P15428 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4593881 1.00 ESR1 (0.40) ESR1CNR2CNR1SMPD1TRPV1
SCHEMBL9562068 0.91 RIPK1 (0.36) ESR1TRPV1BCHEACHE
SCHEMBL9562061 0.91 RIPK1 (0.36) ESR1TRPV1BCHEACHE
SCHEMBL9346287 0.89 L3MBTL1 (0.41) PPARGPTGESALOX5HPGD
SCHEMBL9346299 0.89 L3MBTL1 (0.41) PPARGPTGESALOX5HPGD
SCHEMBL9723164 0.88 S1PR5 (0.41) ESR1CNR2CNR1SMPD1PPARG
SCHEMBL9723248 0.87 S1PR5 (0.43) ESR1CNR2CNR1SMPD1
SCHEMBL9419280 0.87 S1PR5 (0.38) CNR2CNR1PPARGPTGESALOX5
SCHEMBL9723176 0.87 S1PR5 (0.43) ESR1CNR2CNR1SMPD1
SCHEMBL9590535 0.85 L3MBTL1 (0.38) PPARGPTGESALOX5HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1187802-B1 LIQUID CRYSTAL COMPOUNDS ROLIC AG (CH) 2008-01-02 EP disclosed
US-6746729-B1 COMPONENTS OF POLYMERIZABLE LIQUID CRYSTALLINE MIXTURES IN PRODUCTION OF ORIENTATED LIQUID CRYSTALLINE POLYMER NETWORKS ROLIC AG (CH) 2004-06-08 US disclosed
EP-1046631-A1 Liquid crystalline compounds Rolic AG (CH) 2000-10-25 EP disclosed