Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | MC4R | P32245 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | PRNP | P04156 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.42 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12046421 | 0.82 | BRD4 (0.47) | BRD4KMT2AMC4RKDM4EHSD17B10 | |
| Hydrochloric Acid SCHEMBL4345829 | 0.80 | BRD4 (0.57) | BRD4KMT2AMC4RKDM4EHSD17B10 | |
| SCHEMBL28810308 | 0.79 | P2RX4 (0.50) | KMT2AKDM4EALDH1A1LMNAHPGD | |
| SCHEMBL28265879 | 0.79 | KMT2A (0.42) | KMT2AKDM4EALDH1A1KCNN4CYP1A2 | |
| SCHEMBL9731132 | 0.79 | KCNN4 (0.47) | KMT2AKDM4EALDH1A1KCNN4CYP1A2 | |
| SCHEMBL10773261 | 0.79 | BRD4 (0.47) | BRD4MC4RKDM4EALDH1A1HPGD | |
| SCHEMBL13587950 | 0.78 | BRD4 (0.56) | BRD4KMT2AKDM4EALDH1A1CYP1A2 | |
| SCHEMBL27949777 | 0.76 | ATP4A (0.48) | KMT2AKDM4EKCNN4CYP1A2CYP3A4 | |
| SCHEMBL28852239 | 0.76 | P2RX4 (0.49) | KMT2AMC4RALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL877718 | 0.75 | BRD4 (0.53) | BRD4KMT2AMC4RKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105229009-A | 2-phenylimidazo [1,2-A ] pyrimidines as imaging agents | HOFFMANN LA ROCHE | 2016-01-06 | — | — | CN | claimed |
| CN-105229009-A | 2-phenylimidazo [1,2-A ] pyrimidines as imaging agents | HOFFMANN LA ROCHE | 2016-01-06 | — | — | CN | disclosed |