Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27949777 | 0.91 | ATP4A (0.48) | KCNN4KMT2AP2RX4KDM4EKDR | |
| SCHEMBL28810308 | 0.84 | P2RX4 (0.50) | KMT2AP2RX4SMN1; SMN2GAAMEN1 | |
| SCHEMBL10904420 | 0.82 | GAA (0.47) | KMT2ASMN1; SMN2GAAMEN1HCAR1 | |
| SCHEMBL28050388 | 0.79 | BRD4 (0.50) | KCNN4KMT2ASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL28265879 | 0.78 | KMT2A (0.42) | KCNN4KMT2ASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL7426505 | 0.75 | CYP1A2 (0.59) | KMT2ASMN1; SMN2GAAMEN1HCAR1 | |
| SCHEMBL28807183 | 0.73 | KDR (0.40) | KMT2AP2RX4SMN1; SMN2GAAKDM4E | |
| SCHEMBL11878614 | 0.72 | AKT1 (0.41) | CYP1A2CYP3A4CYP2D6CYP2C19LMNA | |
| SCHEMBL15921161 | 0.72 | SMN1; SMN2 (0.42) | KMT2ASMN1; SMN2GAAMEN1HCAR1 | |
| SCHEMBL15921015 | 0.72 | SMN1; SMN2 (0.42) | KMT2ASMN1; SMN2GAAMEN1HCAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5116934-A | Polyethers | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF THE NATIONAL AERONAUTICS AND SPACE ADMINISTRATION (US) | 1992-05-26 | — | — | US | disclosed |
| US-5066811-A | Di(hydroxyphenyl)imidazole monomers used to make polyethers | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF THE NATIONAL AERONAUTICS AND SPACE ADMINISTRATION (US) | 1991-11-19 | — | — | US | disclosed |